Randomized phase III trial of postoperative whole brain radiation therapy compared with salvage stereotactic radiosurgery in patients with one to four brain metastasis: Japan Clinical Oncology Group Study (JCOG 0504)

Phase 3

• Conditions: brain neoplasms/secondary

• Registration Number: JPRN-C000000307
• Lead Sponsor: Japan Clinical Oncology Group(JCOG)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-01-18
• Study Completion: 2015-06-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 270

Inclusion Criteria

Not provided

Exclusion Criteria

(1) synchronous or metachronous (within 5 years) malignancy other than carcinoma in situ or mucosal cancer (2) pregnant or breast-feeding women (3) severe mental disease (4) allergic to gadolinium contained contrast agents

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
overall survival

Secondary Outcome Measures

Name	Time	Method
proportion of performance status (PS) preservation, proportion of mini-mental status examination (MMSE) preservation, and adverse events.