ACTRN12623000121662尚未招募未知
A stepped wedge cluster randomised trial to compare the effect of A Systems aPproach to community-based medIcation REview with usual care on unplanned, all-cause hospital readmissions in people at risk of medication harm after a hospital stay: ASPIRE trial
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 入组人数
- 2,112
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 45 Years 至 o limit（—）
- 性别
- All
入选标准
- •Adult hospital in-patients who
- •1.Reside in the Primary Health Network of the hospital site.
- •2.Have a Medicare card
- •3Have a nominated GP or nominated general practice in the Primary Health Network
- •4.Have a nominated community pharmacy in the Primary Health Network
- •5.Meet one or more of the following:
- •i.) Admission is due to a medication-related problem (as recorded in patient’s notes or identified during ward round)
- •ii.) Is taking 10 or more medicines (including PRN)
- •iii.) Has been started on 1 or more high-risk medicines during admission
- •iv.) Has had 4 or more changes made to medicines during admission
- •v.) Has had 1 or more change to a high-risk medicine or to a falls risk increasing medicine during admission
- •vi.) Is taking 2 or more falls risk increasing, anticholinergic or sedative medicines on discharge
- •vii.) Has difficulty managing medicines, as assessed by patient, GP, medical team or pharmacist, due to 1 or more of: (a) literacy or language; (b) dexterity or vision or frailty or mobility; (c) cognitive impairment or confusion or dementia; or (d) access to medicines (e.g., financial)
- •Definitions
- •High risk medicines include but are not limited to insulins, anticoagulants, oral hypoglycaemics, dual antiplatelet therapy, digoxin, opioids, oral cytotoxics, sedatives, hypnotics, anxiolytics, antipsychotics, anticholinergic medicines
- •Falls-risk increasing medicines include but are not limited to medicines listed in the NSW TAG Medication-related Falls Risk Assessment Tool.
- •Anticholinergic medicines include but are not limited to medicines listed in 'Drugs with anticholinergic effects', Australian Medicines Handbook
- •Sedative medicines include but are limited to medicines listed in 'Drugs for Anxiety and sleep disorders', Australian Medicines Handbook
排除标准
- •Individuals will be excluded if they
- •1.are younger than 45 years of age.
- •2.are receiving active radiation therapy or chemotherapy for malignant conditions
- •3.have been admitted for planned dialysis
- •4.are in terminal phase of palliative care
- •5.are unable to attend Medication Management Review within the time frame
- •6.have previously been recruited to ASPIRE trial
- •7.are being transferred to a rehabilitation, private or other hospital
研究者
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