Opioid free anesthesia: A safer option in obese patients.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Primary Outcome: Postoperative consumption of narcotic in recovery room during 24 hours post operatively.
研究概览
简要总结
This was a prospective, randomized, double blind controlled study on a total of 80 patients of age 20 to 60 years with ASA II or III physical status and BMI of 30 or more scheduled for laproscopic urological procedures under general anaesthesia.
The objective of this study was to evaluate efficacy of Opioid Free Anaesthesia with propofol, dexmedetomidine, lignocaine and ketamine in obese patients posted for urological laproscopic procedures and its effects on postoperative analgesic consumption, haemodynamic stability and incidence of respiratory depression.
Postoperative pain was assessed using Visual Analogue Score (VAS) 30 minutes after recovery, hourly after 2 hours and every 4hourly for 24 hours. Mean analgesic consumption, time of rescue analgesic administration, PACU discharge times were also noted.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of age 20 to 60 years scheduled for laproscopic urological procedure BMI > 30.
排除标准
- •Patients with history of known allergies to study drugs Opioid use one month prior to surgery Chronic opioid addiction Inability to comprehend visual analog scale Pregnant or lactating mothers History of significant hepatic, renal or cardiac disease.
结局指标
主要结局
Primary Outcome: Postoperative consumption of narcotic in recovery room during 24 hours post operatively.
时间窗: 24 hours post operatively
Secondary outcomes:
时间窗: 24 hours post operatively
Time of first rescue analgesic administration, extubation, orientation and PACU discharge times
时间窗: 24 hours post operatively
次要结局
- Secondary outcomes:(Time of first rescue analgesic administration, extubation, orientation and PACU discharge times)