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Clinical Trials/NCT04925739
NCT04925739
Completed
Not Applicable

Evaluation of the Comfort of a Continuous Positive Airway Pressure Nasal Mask in the Treatment of Obstructive Sleep Apnea Syndrome

AGIR à Dom1 site in 1 country20 target enrollmentSeptember 22, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Apnea, Obstructive
Sponsor
AGIR à Dom
Enrollment
20
Locations
1
Primary Endpoint
To evaluate the comfort and general appreciation of a nasal mask
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep apnea syndrome (OSA). It consists of a pressure generator connected to a mask applied to the patient's face. CPAP treatment is restrictive, and nearly a quarter of patients abandon it over the long term. Various factors can influence adherence to CPAP therapy, including adverse events associated with the mask. However, it is clear that compliance with CPAP treatment, even if it has tended to improve over the last 30 years, is still sub-optimal.

The "Air Liquide Medical Systems" company has developed a mask that aims to improve comfort and ease of use for the patient. This leaky nasal mask has a "silent" intentional leak port, which significantly reduces the noise caused by the escape of air. The noise associated with intentional leakage is one of the discomforts reported by patients and their spouses. In addition, this mask is equipped with a new generation headgear with adjustment indicators to assist the patient in fitting the mask. Optimal headgear fit is a prerequisite for comfort during treatment, as it reduces unintentional leakage.

The main objective is to evaluate, through a questionnaire, the comfort and general appreciation of a nasal mask equipped with a silent leak system and a headgear with adjustment aids, of patients with OSA treated with CPAP.

Secondary objectives are :

  1. To evaluate the appearance of CPAP side effects related to the mask,
  2. To collect the patient's appreciation of the mask headgear,
  3. To evaluate the discomfort caused by the nasal obstruction reported by the patient,
  4. To evaluate the daytime sleepiness of the patient,
  5. To study the parameters of the CPAP treatment.

Detailed Description

Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep apnea syndrome (OSA). It consists of a pressure generator connected to a mask applied to the patient's face. CPAP treatment is restrictive, and nearly a quarter of patients abandon it over the long term. Various factors can influence adherence to CPAP therapy, including adverse events associated with the mask. Unintentional leaks, i.e. a leak between the pressure generator and the patient's upper airway, are among the most frequent. Therefore, optimizing the choice of mask is one of the main means used by medical-technical providers, in charge of installing CPAP and its technical follow-up at home. In order to cover the needs and anatomical particularities of the OSA patient population treated with CPAP, a large number of mask types and sizes are currently available on the market. However, it is clear that compliance with CPAP treatment, even if it has tended to improve over the last 30 years, is still sub-optimal. The "Air Liquide Medical Systems" company has developed a mask that aims to improve comfort and ease of use for the patient. This leaky nasal mask has a "silent" intentional leak port, which significantly reduces the noise caused by the escape of air. The noise associated with intentional leakage is one of the discomforts reported by patients and their spouses. In addition, this mask is equipped with a new generation headgear with adjustment indicators to assist the patient in fitting the mask. Optimal headgear fit is a prerequisite for comfort during treatment, as it reduces unintentional leakage. The main objective is to evaluate, through a questionnaire, the comfort and general appreciation of a nasal mask equipped with a silent leak system and a headgear with adjustment aids, of patients with OSA treated with CPAP. After 30 days of use, secondary objectives are : 1. To evaluate the appearance of CPAP side effects related to the mask (air leaks, injury to the nasal bridge, etc.) 2. To collect the patient's appreciation of the mask headgear, which includes indications to help with the installation in the form of graduated markers, as well as the appreciation of the general aesthetics of the mask. 3. To evaluate the discomfort caused by the nasal obstruction reported by the patient, in relation to the inclusion. 4. To evaluate the daytime sleepiness of the patient, compared to the inclusion. 5. To study the parameters of the CPAP treatment.

Registry
clinicaltrials.gov
Start Date
September 22, 2021
End Date
January 21, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
AGIR à Dom
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Male or female patient over 18 years of age
  • Patient with OSA
  • Patient not previously treated with CPAP
  • A patient who will be treated with a "ResMed Airsense 10" CPAP and an "Air Liquide Medical Systems" NINA mask
  • Patient whose CPAP treatment will be installed and monitored by the home care provider AGIRADOM
  • Patient willing to participate in the research after adequate information and delivery of the information note
  • Patient affiliated to the social security system or beneficiary of such a system

Exclusion Criteria

  • NOSE questionnaire score greater than or equal to 10/20 at the time of CPAP installation
  • Patient with significant craniofacial deformities that do not allow the mask to be fitted correctly
  • Person deprived of liberty by judicial or administrative decision, person under legal protection (patient under guardianship or curators) Article L1121-8
  • Subject who receives more than 4500 euros in compensation for his or her participation in other research involving the human person in the 12 months preceding this study

Outcomes

Primary Outcomes

To evaluate the comfort and general appreciation of a nasal mask

Time Frame: After 30 days of CPAP treatment

to evaluate, through a questionnaire, the comfort and general appreciation of a nasal mask equipped with a silent leak system and a headgear with adjustment aids, of patients with OSA treated with CPAP.

Secondary Outcomes

  • To evaluate the appearance of CPAP side effects related to the mask(After 30 days of CPAP treatment)
  • To collect the patient's appreciation of the mask headgear(After 30 days of CPAP treatment)
  • To evaluate the discomfort caused by the nasal obstruction reported by the patient(After 30 days of CPAP treatment)
  • To evaluate the daytime sleepiness of the patient(After 30 days of CPAP treatment)
  • To collect the CPAP treatment compliance(During the 30 days of CPAP treatment)
  • To collect the unintentional leakage(During the 30 days of CPAP treatment)
  • To collect the CPAP therapeutic pressures(During the 30 days of CPAP treatment)

Study Sites (1)

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