Detection of markers for immune pathophysiology and analysis of their prognostic value in patients with chronic thrombocytopenia without an increase in the number of bone marrow megakaryocytes: a prospective observation study.
Not Applicable
Recruiting
- Conditions
- Pancytopenia, thrombocytopenia
- Registration Number
- JPRN-UMIN000002729
- Lead Sponsor
- Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients treated by immunosuppressive therapy. 2) Patients with a history of hematologic malignancy. 3) Patients with malignancies requiring treatment.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survival of the 'TDM' patients, maintaining the number of platelets greater than 5.0x10e4/mcl.
- Secondary Outcome Measures
Name Time Method 1) Changes of the severity of the diseases graded by the clinical stratification for aplastic anemia. 2) Frequency of patients, positive for PNH-type cells. 3) The choice of treatment selected by attending physician.