ACTRN12606000161527
Withdrawn
Not Applicable
Randomised double-blind placebo controlled trial of pyridoxine for prevention of capecitabine induced hand-foot syndrome
Dr Chris Karapetis0 sites288 target enrollmentMay 8, 2006
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Capecitabine induced hand-foot syndrome (HFS)
- Sponsor
- Dr Chris Karapetis
- Enrollment
- 288
- Status
- Withdrawn
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Commencement of capecitabine at a dose of 800mg/m2 BD every 2 out of 3 weeks either as single agent or combination therapySigned informed consent. Life expectancy greater than 12 weeksConcommitant radiotherapy or steroids permitted
Exclusion Criteria
- •Prior capecitabine chemotherapy over the past 30 daysInability to provide informed consentConcommitant administration of drugs that cause HFS eg docetaxel, liposomal doxorubicinConsumption of pyridoxine\-containing preparationsAnticipated inability to follow up patient for side effects of chemotherapy.
Outcomes
Primary Outcomes
Not specified
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