MedPath

Stress Management Therapy in Patients Receiving Chemotherapy for Cancer

Not Applicable
Completed
Conditions
Cancer
Psychological Stress
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
Other: Self Administered Stress Management
Registration Number
NCT00377130
Lead Sponsor
University of South Florida
Brief Summary

RATIONALE: A stress-management program may improve quality of life and reduce anxiety and depression in patients receiving chemotherapy for cancer.

PURPOSE: This randomized clinical trial is studying how well stress management therapy works in patients receiving chemotherapy for cancer.

Detailed Description

OBJECTIVES:

Primary

* Determine if a self-administered stress management intervention is effective in improving quality of life and decreasing psychological distress (anxiety and depression) in Hispanic and non-Hispanic patients receiving cancer chemotherapy.

Secondary

* Determine if the degree of acculturation in Hispanics influences the observed helpfulness of the intervention.

OUTLINE: This is a randomized, multicenter study. Patients are stratified according to participating center, use of psychotropic drugs (yes vs no), and ethnicity (Hispanic vs non-Hispanic). Patients are randomized to 1 of 2 arms.

* Arm I (self-administered stress management training plus usual psychosocial care): Patients receive a video DVD, audio CD, and brochure that provides information and instruction in 3 stress management training techniques (progressive muscle relaxation training and guided imagery, abdominal breathing, and coping skills training) to use during chemotherapy. Patients also receive usual psychosocial care.

* Arm II (usual psychosocial care only): Patients receive usual psychosocial care.

Patients complete questionnaires to assess mood, quality of life, and other factors at baseline and before chemotherapy courses 2, 3, and 4.

PROJECTED ACCRUAL: A total of 442 patients will be accrued for this study.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
442
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Self administered Stress ManagementSelf Administered Stress ManagementSelf-Administered Stress Management Training Plus Usual Psychosocial Care
Primary Outcome Measures
NameTimeMethod
Quality of lifeAfter 4th chemotherapy cycle

Assessed at baseline (before first chemotherapy cycle) and just before the start of the second, third and fourth chemotherapy cycles.

Anxietyafter 4th chemotherapy cycle

Assessed at baseline (before first chemotherapy cycle) and just before the start of the second, third and fourth chemotherapy cycles.

DepressionAfter 4th chemotherapy cycle

Assessed at baseline (before first chemotherapy cycle) and just before the start of the second, third and fourth chemotherapy cycles.

Secondary Outcome Measures
NameTimeMethod
Degree of acculturationAfter 4th chemotherapy cycle

Assessed at baseline (before first chemotherapy cycle) and just before the start of the second, third and fourth chemotherapy cycles.

Trial Locations

Locations (51)

Feist-Weiller Cancer Center at Louisiana State University Health Sciences

๐Ÿ‡บ๐Ÿ‡ธ

Shreveport, Louisiana, United States

MBCCOP - JHS Hospital of Cook County

๐Ÿ‡บ๐Ÿ‡ธ

Chicago, Illinois, United States

CCOP - Beaumont

๐Ÿ‡บ๐Ÿ‡ธ

Royal Oak, Michigan, United States

St. John's Regional Health Center

๐Ÿ‡บ๐Ÿ‡ธ

Springfield, Missouri, United States

Newark Beth Israel Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Newark, New Jersey, United States

CCOP - Bay Area Tumor Institute

๐Ÿ‡บ๐Ÿ‡ธ

Oakland, California, United States

CCOP - Southeast Cancer Control Consortium

๐Ÿ‡บ๐Ÿ‡ธ

Goldsboro, North Carolina, United States

Contra Costa Regional Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Martinez, California, United States

Adena Regional Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Chillicothe, Ohio, United States

Hulston Cancer Center at Cox Medical Center South

๐Ÿ‡บ๐Ÿ‡ธ

Springfield, Missouri, United States

CCOP - Cancer Research for the Ozarks

๐Ÿ‡บ๐Ÿ‡ธ

Springfield, Missouri, United States

Mount Carmel Hospital East

๐Ÿ‡บ๐Ÿ‡ธ

Columbus, Ohio, United States

Pardee Memorial Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Hendersonville, North Carolina, United States

High Point Regional Hospital

๐Ÿ‡บ๐Ÿ‡ธ

High Point, North Carolina, United States

Licking Memorial Cancer Care Program at Licking Memorial Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Newark, Ohio, United States

CCOP - Columbus

๐Ÿ‡บ๐Ÿ‡ธ

Columbus, Ohio, United States

Hato Rey Hematology/Oncology Group, PSC

๐Ÿ‡ต๐Ÿ‡ท

San Juan, Puerto Rico

Genesis - Good Samaritan Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Zanesville, Ohio, United States

Scott and White Cancer Institute

๐Ÿ‡บ๐Ÿ‡ธ

Temple, Texas, United States

Roger Maris Cancer Center at MeritCare Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Fargo, North Dakota, United States

CCOP - MeritCare Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Fargo, North Dakota, United States

MeritCare Bemidji

๐Ÿ‡บ๐Ÿ‡ธ

Bemidji, Minnesota, United States

Andres Grillasca Hospital

๐Ÿ‡ต๐Ÿ‡ท

Ponce, Puerto Rico

Bay Area Tumor Institute

๐Ÿ‡บ๐Ÿ‡ธ

Oakland, California, United States

Iredell Memorial Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Statesville, North Carolina, United States

Mount Carmel Health - West Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Columbus, Ohio, United States

Doctors Hospital at Ohio Health

๐Ÿ‡บ๐Ÿ‡ธ

Columbus, Ohio, United States

Rainier Physicians - NWMS

๐Ÿ‡บ๐Ÿ‡ธ

Puyallup, Washington, United States

Louisiana State University Health Sciences Center - Monroe

๐Ÿ‡บ๐Ÿ‡ธ

Monroe, Louisiana, United States

Dickstein Cancer Treatment Center at White Plains Hospital Center

๐Ÿ‡บ๐Ÿ‡ธ

White Plains, New York, United States

Southeastern Medical Oncology Center - Goldsboro

๐Ÿ‡บ๐Ÿ‡ธ

Goldsboro, North Carolina, United States

Riverside Methodist Hospital Cancer Care

๐Ÿ‡บ๐Ÿ‡ธ

Columbus, Ohio, United States

Southeastern Medical Oncology Center - Wilson

๐Ÿ‡บ๐Ÿ‡ธ

Wilson, North Carolina, United States

Grant Medical Center Cancer Care

๐Ÿ‡บ๐Ÿ‡ธ

Columbus, Ohio, United States

Mount Carmel St. Ann's Cancer Center

๐Ÿ‡บ๐Ÿ‡ธ

Columbus, Ohio, United States

Springfield Regional Cancer Center

๐Ÿ‡บ๐Ÿ‡ธ

Springfield, Ohio, United States

Strecker Cancer Center at Marietta Memorial Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Marietta, Ohio, United States

CCOP - Northwest

๐Ÿ‡บ๐Ÿ‡ธ

Tacoma, Washington, United States

CCOP - Scott and White Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Temple, Texas, United States

John H. Stroger, Jr. Hospital of Cook County

๐Ÿ‡บ๐Ÿ‡ธ

Chicago, Illinois, United States

Forsyth Regional Cancer Center at Forsyth Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Winston-Salem, North Carolina, United States

Our Lady of Mercy Medical Center Comprehensive Cancer Center

๐Ÿ‡บ๐Ÿ‡ธ

Bronx, New York, United States

Savoy Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Mamou, Louisiana, United States

Veterans Affairs Medical Center - Shreveport

๐Ÿ‡บ๐Ÿ‡ธ

Shreveport, Louisiana, United States

I. Gonzalez Martinez Oncologic Hospital

๐Ÿ‡ต๐Ÿ‡ท

San Juan, Puerto Rico

William Beaumont Hospital - Royal Oak Campus

๐Ÿ‡บ๐Ÿ‡ธ

Royal Oak, Michigan, United States

Howard University Cancer Center

๐Ÿ‡บ๐Ÿ‡ธ

Washington, District of Columbia, United States

William Beaumont Hospital - Troy Campus

๐Ÿ‡บ๐Ÿ‡ธ

Troy, Michigan, United States

Veterans Affairs Medical Center - San Juan

๐Ÿ‡ต๐Ÿ‡ท

San Juan, Puerto Rico

San Juan City Hospital

๐Ÿ‡ต๐Ÿ‡ท

San Juan, Puerto Rico

Grady Memorial Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Delaware, Ohio, United States

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