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Investigation of the efficacy of a herbal topical gel in reducing the skin reactions in cancer patients taking chemotherapy drugs Fluoropyrimidines induced Hand-Foot Syndrome in cancerous patients

Phase 1
Conditions
hand-foot syndrome.
localized skin eruption due to drugs and medicaments
Registration Number
IRCT2014051017643N1
Lead Sponsor
Pharmaceutical Sciences branch, Islamic Azad University(a part of razieh mohajerani's PharmD thesis
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Taking 5-fluorouracil (5-fu) by injection or oraly Capecitabine as an anticancer drug; showing hand-foot syndrome; patient satisfaction; Having cancer. Exclusion criteria: Treatment change and discontinuing 5-fluorouracil (5-fu) and oral Capecitabine administration; Showing no hand-foot syndrome; Patient's death; Lack of cancer; Sensitivity to compounds of formula.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Severity of HFS symptoms. Timepoint: Beginning of the study , the fourteenth day. Method of measurement: NCI Hand-Foot Syndrome staging version 4.0.
Secondary Outcome Measures
NameTimeMethod
Skin Sensitivity. Timepoint: From the beginning of the study. Method of measurement: Observational.
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