The Synergistic Effect of Dietary Intake of French Maritime Pine bark Extract and Coenzyme Q10 on Skin Elasticity and Hydratio

Phase 4

• Conditions: Healthy woman; Pycnogenol; Coenzyme Q10; Skin elasticity; Skin hydration; Melanin index

• Registration Number: TCTR20210224006
• Lead Sponsor: Pharma Nord S.E.A Co.,Ltd

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-24
• Study Completion: 2021-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: Female
• Target Recruitment: 36

Inclusion Criteria

1. Female volunteers
2. Age 35-45
3. No medical condition, no serious disease or chronic disease those may effect the research
4. Not a menopause
5. Willingness for the study and sign in consent form
6. No history of French Maritime Pine bark extract or Coenzyme Q10 allergy
7. No skin disease, Eczema around the test area
8. Those who had not received an operative facial treatment, such as dermabrasion , Iontophoresis , Radiofrequency within 1 month prior to the research
9. Those who are not taking vitamins supplement, other antioxidants that have the effect of reducing wrinkles or increase skin moisture within 3 months before participating in the research
10. Those who had not received the BOTOX injection around the area to be tested within 8 months prior to the research
11. Those who had not received a Filler injection around the area to be tested within 1 year prior to the research
12. Non smoker or those who do not have regular exposure to sunlight without sunscreen protection
13. No pregnancy and lactation .

Exclusion Criteria

1. Those who need to leave the research
2. Get pregnant during the research
3. Forget to take the tested products more than 1 time a week with follow-up by calling or by LINE application
4. Get BOTOX , FILLER , STEM CELL injection or Laser treatment during the research
5. Change in vitamin or supplement intake habits such as take more than usual or stop taking what they take regularly
6. Allergic to any  ingredient of the tested products

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Skin elasticity at 6 and 8 weeks Cutometer,Skin hydration at 6 and 8 weeks TEWAmeter, Corneometer

Secondary Outcome Measures

Name	Time	Method
Pigmentation at 6 and 8 weeks Mexameter