Effect of direct renin-inhibition aliskiren on renal haemodynamic and metabolic parameters in patients with prediabetes - AMARYLIS

niversity Hospital Erlangen0 个研究点目标入组 20 人开始时间: 2010年4月13日最近更新: 2014年3月31日

试验速览

暂无简介。

•Adults aged > 18 to < 70 years
•Prediabetes (HbA1c 5.7-6.4 %) impaired fasting glucose (blood glucose 100 - 126 mg/dl) or impaired glucose tolerance (IGT) (Blood glucose > 140 mg/dl and < 200 mg/dl 2 h after an oral glucose administration of 75g)
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Diabetes Mellitus Type 1/2
•Micro-, or Macroalbuminuria
•Renal insufficiency
•Secondary forms of arterial hypertension
•Ongoing therapy with ACE-Inhibitors, AT1 blocker, direct renin inhibitor
•Antihypertensive therapy with more than 2 agents
•Uncontrolled Blood pressure
•Known intolerance of direct renin inhibitor
•Medical history of cerebral stroke or myocardial infarction within the last 6 months, chronic heart failure NYHA III-IV
•Severe gastrointestinal disease
•Elevated liver parameters (SGOT, SGPT > more than doubled)
•Tablet or alcohol abuse
•Adipositas per magna (BMI > 35kg/m²)
•Malignant disease
•Insufficient Compliance

发起方

niversity Hospital Erlangen