Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Overall agreement established by interclass correlation on the T stage of TNM
研究概览
简要总结
The diagnostic and pre-therapeutic assessment of squamous cell carcinomas requires a neck and chest CT scan and a neck and facial MRI, which is the most effective examination, to establish the TNM stage of the tumor. However, obtaining this complete assessment can delay treatment. Confirmation of the non-inferiority of 40keV dual-energy CT in BOLT compared to MRI would spare the patient an additional MRI examination, speed up the pre-treatment assessment, reduce the loss of opportunity due to delayed treatment, and free up MRI imaging slots, which are still insufficient in the region.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patient (≥18 years)
- •presenting with oral or oropharyngeal squamous cell carcinoma proven by histopathological analysis of a biopsy
- •having undergone a clinical examination with nasofibroscopy by an ENT surgeon specializing in cancer surgery
- •a contrast-enhanced cervicofacial MRI
- •and a contrast-enhanced cervicofacial DECT with BOLT maneuver.
排除标准
- •A lesion other than oral or oropharyngeal squamous cell carcinoma
- •A labial location
- •A contraindication to performing one or both of the imaging examinations.
结局指标
主要结局
Overall agreement established by interclass correlation on the T stage of TNM
时间窗: Up to 12 months
Overall agreement established by interclass correlation on the T stage of TNM between the radiological analysis of the DECT 40 kev BOLT, and of the MRI, compared to the reference T stage of TNM from the RCP: Overall agreement: This means: do the methods give the same results? We want to know if DECT and MRI reach the same T stage for the same patient. Example: DECT: T3 MRI: T3 Result: Good agreement DECT: T2 MRI: T3 Result: Disagreement
次要结局
未报告次要终点