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Clinical Trials/NCT05897502
NCT05897502
Completed
Not Applicable

A 34-Week Single-Blind Trial of Explore the Effectors of The Transtheoretical Model on Nutritional Education in Patients on Hemodialysis

Liu, Liu-Yin1 site in 1 country43 target enrollmentJuly 4, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
End-Stage Kidney Disease
Sponsor
Liu, Liu-Yin
Enrollment
43
Locations
1
Primary Endpoint
Change from Baseline in Biochemical value( normalized protein catabolic rate) at the third month
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to assess the improvement degree of nutritional care program on the nutritional status and eating habits of hemodialysis patients

Detailed Description

After being informed about the study and potential risks, all patients giving written Informed consent will undergo a 1-week screening period to determine eligibility For study entry. At week 0, eligible patients will be assigned to the intervention group and the control group by single-blind manner(participant) with convenience sampling. In the intervention group, the patients were trained in The Transtheoretical Model on nutritional education for 8 weeks. In the control group, the patients were trained in roution nutrition education.

Registry
clinicaltrials.gov
Start Date
July 4, 2023
End Date
February 29, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Liu, Liu-Yin
Responsible Party
Sponsor Investigator
Principal Investigator

Liu, Liu-Yin

Nurse

E-DA Hospital

Eligibility Criteria

Inclusion Criteria

  • the biochemical value ≥ 5.5 mg/dl or albumin value\<3.8g/dL
  • BMI\<23kg/m2
  • Unexpected weight loss.
  • Must be able to swallow tablets

Exclusion Criteria

  • Clinical diagnosis of Alzheimer's Disease
  • Malignant tumors, gastrointestinal cachexia, and catheterization

Outcomes

Primary Outcomes

Change from Baseline in Biochemical value( normalized protein catabolic rate) at the third month

Time Frame: Baseline and the third month

Biochemical value( normalized protein catabolic rate) is a validated to assess the nutritional status of hemodialysis, normal value greater than 1.2gm/day/k

Change from Baseline in Biochemical value(cholesterol )at the fourth month

Time Frame: Baseline and the fourth month

Biochemical value( cholesterol) is a validated to assess the nutritional status of hemodialysis, less than 100mg/dl is considered malnutrition

Change from Baseline in Biochemical value( Phosphate) at the fourth month

Time Frame: Baseline and the fourth month

Biochemical value(Phosphate) is a validated to assess the nutritional status of hemodialysis, normal value is 2.7-4.5 mg/dL

Change from Baseline in (Mini Nutritional Assessment-Short Form, MNA-SF) at the fourth month

Time Frame: Baseline and the fourth month

(Mini Nutritional Assessment-Short Form, MNA-SF) is a validated self-reported instrument to assess the nutritional status of hemodialysis,Out of 14 points. ≤11 points malnutrition risk. ≤7 points malnutrition.

Change from Baseline in Biochemical value (Albumine) at the fourth month

Time Frame: Baseline and the fourth month

Biochemical value (Albumine) is a validated to assess the nutritional status of hemodialysis, less than 3.8gm/dl is considered malnutrition

Change from Baseline in Biochemical value (Albumine) at the sixth month

Time Frame: Baseline and the sixth month

Biochemical value (Albumine) is a validated to assess the nutritional status of hemodialysis, less than 3.8gm/dl is considered malnutrition

Change from Baseline in Biochemical value( normalized protein catabolic rate) at the fourth month

Time Frame: Baseline and the fourth month

Biochemical value( normalized protein catabolic rate) is a validated to assess the nutritional status of hemodialysis, normal value greater than 1.2gm/day/k

Change from Baseline in Biochemical value(cholesterol )at the third month

Time Frame: Baseline and the third month

Biochemical value( cholesterol) is a validated to assess the nutritional status of hemodialysis, less than 100mg/dl is considered malnutrition

Change from Baseline in Biochemical value(cholesterol )at the sixth month

Time Frame: Baseline and and the sixth month

Biochemical value( cholesterol) is a validated to assess the nutritional status of hemodialysis, less than 100mg/dl is considered malnutrition

Change from Baseline in Biochemical value (Albumine) at the third month

Time Frame: Baseline and the third month

Biochemical value (Albumine) is a validated to assess the nutritional status of hemodialysis, less than 3.8gm/dl is considered malnutrition

Change from Baseline in Biochemical value( normalized protein catabolic rate) at the sixth month

Time Frame: Baseline and the sitxth month

Biochemical value( normalized protein catabolic rate) is a validated to assess the nutritional status of hemodialysis, normal value greater than 1.2gm/day/k

Change from Baseline in body measurement ( Hand grip strength ) at the fourth month

Time Frame: Baseline and the fourth month

Hand grip strength is a validated to assess the nutritional status of hemodialysis, male ≤ 30 kilograms, female ≤ 20 kilograms, indicating a risk of frailty

Change from Baseline in (Mini Nutritional Assessment-Short Form, MNA-SF) at the third month

Time Frame: Baseline and the third month

(Mini Nutritional Assessment-Short Form, MNA-SF) is a validated self-reported instrument to assess the nutritional status of hemodialysis,Out of 14 points. ≤11 points malnutrition risk. ≤7 points malnutrition.

Change from Baseline in Biochemical value(creatine)at the third month

Time Frame: Baseline and the third month

Biochemical value(creatine) is a validated to assess the nutritional status of hemodialysis, less than 8-10 mg/dl before hemodialysis indicates malnutrition

Change from Baseline in Biochemical value(creatine) at the fourth month

Time Frame: Baseline and the fourth month

Biochemical value(creatine) is a validated to assess the nutritional status of hemodialysis, less than 8-10 mg/dl before hemodialysis indicates malnutrition

Change from Baseline in body measurement ( Hand grip strength ) at the sixth month

Time Frame: Baseline and the sixth month

Hand grip strength is a validated to assess the nutritional status of hemodialysis, male ≤ 30 kilograms, female ≤ 20 kilograms, indicating a risk of frailty

Change from Baseline in Biochemical value(creatine) at the sixth month

Time Frame: Baseline and the sixth month

Biochemical value(creatine) is a validated to assess the nutritional status of hemodialysis, less than 8-10 mg/dl before hemodialysis indicates malnutrition

Change from Baseline in Biochemical value( Phosphate) at the third month

Time Frame: Baseline and the third month

Biochemical value(Phosphate) is a validated to assess the nutritional status of hemodialysis, normal value is 2.7-4.5 mg/dL

Change from Baseline in Biochemical value( Phosphate) at the sixth month

Time Frame: Baseline and the sixth month

Biochemical value(Phosphate) is a validated to assess the nutritional status of hemodialysis, normal value is 2.7-4.5 mg/dL

Change from Baseline in body measurement ( Hand grip strength ) at the third month

Time Frame: Baseline and the third month

Hand grip strength is a validated to assess the nutritional status of hemodialysis, male ≤ 30 kilograms, female ≤ 20 kilograms, indicating a risk of frailty

Change from Baseline in (Mini Nutritional Assessment-Short Form, MNA-SF) at the sixth month

Time Frame: Baseline and the six month

(Mini Nutritional Assessment-Short Form, MNA-SF) is a validated self-reported instrument to assess the nutritional status of hemodialysis,Out of 14 points. ≤11 points malnutrition risk. ≤7 points malnutrition.

Secondary Outcomes

  • Change from Baseline in the diet of knowledge form at the fourth month(Baseline and the fourth month)
  • Change from Baseline in the diet of knowledge form at the third month(Baseline and the third month)
  • Change from Baseline in the high phosphorus food frequency questionnaire at the fourth month(Baseline and the fourth month)
  • Change from Baseline in the diet of attitude form at the third month(Baseline and the third month)
  • Change from Baseline in the diet of attitude form at the sixth month(Baseline and the sixth month)
  • Change from Baseline in the high phosphorus food frequency questionnaire at the third month(Baseline and the third month)
  • Change from Baseline in the diet of knowledge form at the sixth month(Baseline and the sixth month)
  • Change from Baseline in the diet of behavior form at the sixth month(Baseline and the sixth month)
  • Change from Baseline in the six major food frequency questionnaire at the third month(Baseline and the third month)
  • Change from Baseline in the six major food frequency questionnaire at the sixth month(Baseline and the sixth month)
  • Change from Baseline in the diet of attitude form at the fourth month(Baseline and the fourth month)
  • Change from Baseline in the diet of behavior form at the third month(Baseline and the third month)
  • Change from Baseline in the diet of behavior form at the fourth month(Baseline and the fourth month)
  • Change from Baseline in the high phosphorus food frequency questionnaire at the sixth month(Baseline and the sixth month)
  • Change from Baseline in the six major food frequency questionnaire at the fourth month(Baseline and the fourth month)

Study Sites (1)

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