Post operative pain management in laparoscopic surgeries

Phase 4

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2022/05/042764

Lead Sponsor: SDMCMSH

Brief Summary: Regional anaesthesia is one of popular methods and has become integral part of both intraoperative anaesthesia and post-operative analgesia.

Wide variety of blocks is being practiced, which avoids polypharmacy, reduces hospital stay and provide good post-operative recovery to the patients.

One such modality which aims at smooth post-op recovery in laparoscopic surgeries is subcostal transverse abdominis plane (TAP) block.

The better outcome of the subcostal TAP block is due to accurate localization of transverse abdominis plane by ultrasound guidance and prolongation of duration of action with help of adjuvants like fentanyl, dexamethasone, clonidine etc. to local anaesthetics.

This study aims to compare the effect of drugs dexamethasone and clonidine as adjuvant to ropivacaine in subcostal TAP block to decrease post-operative pain and to ease the recovery in patients undergoing laparoscopic abdominal surgeries

In this study patients will be randomly allocated in two groups and recieve TAP block at the end of surgery

Group D: Patients in this group will receive TAP block on each side with 0.375% ropivacaine 20 ml along with 1ml (4mg) of dexamethasone as additive

Group C: Patients in this group will receive TAP block on each side with 0.375% ropivacaine 20 ml along with 1mcg/kg of clonidine made to 1ml.

Postoperatively we assess the duration of analgesic effect by addition of dexamethasone and clonidine with ropivacaine in sub costal TAP block. To determine VAS scores in first 24 h. Secondary, Objectives:- 1. To assess incidence of nausea or vomiting or other side effects, if any.

The time at which rescue analgesia administered will be noted. Side effects like bradycardia, hypotension will be monitored and treated as per standard care.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 70

Inclusion Criteria

Patients undergoing elective laparoscopic abdominal surgeries of duration 60-120 mins ASA Physical status 1,2 Those who willing to participate.

Exclusion Criteria

Patient refusal.
Patients with ASA III and IV.
Patients with BMI < 18 kg/m2 and > 35 kg/m2.
Local infection at the site of block.
Allergy to study medications.
6.Chronic use of pain medications.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To compare the duration of analgesic effect by addition of dexamethasone and clonidine with ropivacaine in sub costal TAP block	24 hrs
2. To determine VAS scores in first 24 h.	24 hrs

Secondary Outcome Measures

Name	Time	Method
To assess incidence of nausea or vomiting or other side effects, if any.	24 hrs

Trial Locations

Locations (1): SDM medical college
🇮🇳
Dharwad, KARNATAKA, India
SDM medical college
🇮🇳Dharwad, KARNATAKA, India
Dr Akshatha B
Principal investigator
7829838338
akshathab18@gmail.com