The Prenatal/Early Infancy Project: An Adolescent Follow-up

Not Applicable

Completed

• Conditions: Behavior, Adaptive

• Registration Number: NCT03079752
• Lead Sponsor: University of Colorado, Denver

Brief Summary

The Nurse-Family Partnership, a program of prenatal and infancy home visiting by nurses, has been examined in a series of 3 randomized trials since 1977. It has received considerable attention in the scientific and public policy communities for its replicated effects on a variety of maternal and child health outcomes across these 3 trials, including prenatal health, childhood injuries, rates of subsequent pregnancies, inter-birth intervals, as well as its long-term effects on maternal life-course, criminal behavior, and 15-year-olds' criminal and antisocial behavior in the first trial of the program conducted in Elmira, New York.

Detailed Description

Although this program produced positive effects on maternal and child health from pregnancy through the child's fourth year of life, its long-term effects remain unexamined. The current study was conducted to determine the extent to which the beneficial effects of the program set in motion early in the life cycle altered the life-course trajectories of the mothers and the children's adaptive functioning through the first child's 15th birthday. This study examines the long-term effects of the program on two domains of maternal functioning: 1) maternal life course (subsequent children, use of welfare, employment, substance abuse, and encounters with the criminal justice system); and 2) perpetration of child abuse and neglect; and two domains of the children's behavior: 1) their functioning in schools, and 2) their criminal and antisocial behavior. The investigators hypothesized that the program effects in these domains of maternal and child functioning, as in earlier phases of the study, would be greater for families in which the mothers experienced a larger number of chronic stressors and had fewer resources to manage the challenges of living in poverty and being a parent.

Study Timeline

• Study Start: 1994-03-18
• Primary Completion: 1996-09-12
• Study Completion: 1998-04-30
• Status Verified: 2017-03
• Study First Submitted: 2017-03-08
• Study First Submitted QC: 2017-03-08
• Last Update Submitted: 2017-03-13
• Study First Posted: 2017-03-14
• Last Update Posted: 2017-03-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 629

Inclusion Criteria

Must be offspring of mothers who enrolled in Elmira randomized clinical trial of the Nurse-Family Partnership (known as the Prenatal Early Infancy Project) -

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Timing of Subsequent Births - Mothers	15 years following birth of first child	Interval in days between birth date of first child and first subsequent child (self-reported)
Months Received Aid to Families with Dependent Children (AFDC) - Mothers	15-year interval following birth of first child	Number of months mother received AFDC (self-reported)
Number of Months Employed - Mothers	15-year interval following birth of first child	Number of months employed (self-reported)
Substance Abuse - Mothers	15-year period following birth of first child	Count of behavioral impairments due to use of substances (self-reported)
Arrests - Mothers	15-year interval following birth of first child	Count of arrests (self-reported)
Child Maltreatment Reports - Mothers	15-year interval following birth of first child	Count of substantiated reports of child abuse and neglect in which mother was perpetrator (review of records)
Running Away from Home - Children	15-year interval following birth of first child	Count of times ran away from home - self-report
Person in Need of Supervision (PIN) - Children	15-year period following their birth	Self report of ever having been adjudicated as a PIN
Arrests - Children	15-year period following birth	Count of Arrests - self-report