“Comparative effects of two different doses of fentanyl on attenuation of hemodynamic response to laryngoscopy and tracheal intubation: a prospective, randomized, control trialâ€
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Attenuation of haemodynamic stress response during laryngoscopy and endotracheal intubation which can be assesed
研究概览
简要总结
This study will be carried out in government medical collegevadodara.Overall purpose to carry out this study is to know the effect oftwo different doses(2.5 and 5mcg/kg) of Fentanyl on haemodynamic responses tolaryngoscopy and endotracheal intubation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients posted for elective surgery under General anaesthesia requiring intubation and expected to last for more than one hour ASA status I, II and III Mallampatti airway assessment of Grade I and II.
排除标准
- •Patients who refuse to give consent Anticipated difficult airway Patient having severe uncontrolled cardiovascular disease, respiratory disease, hepatic disease, central nervous system disease or renal disease that is constant threat to life of the patient.
结局指标
主要结局
Attenuation of haemodynamic stress response during laryngoscopy and endotracheal intubation which can be assesed
时间窗: First 10 minutes after laryngoscopy and tracheal intubation
by measuring following parameters:
时间窗: First 10 minutes after laryngoscopy and tracheal intubation
b) Systolic blood pressure/Diastolic blood pressure
时间窗: First 10 minutes after laryngoscopy and tracheal intubation
a)Heart rate
时间窗: First 10 minutes after laryngoscopy and tracheal intubation
c) Mean arterial pressure
时间窗: First 10 minutes after laryngoscopy and tracheal intubation
d) Rate pressure product
时间窗: First 10 minutes after laryngoscopy and tracheal intubation
次要结局
- Reduced incidence of intraoperative complication in the form of pain on injection ,myoclonus, apnea, hypotension, bradycardia and tachycardia.(First 10 minutes after laryngoscopy and tracheal intubation)