Impact of Prokinetic Use After Emergency Intestinal Anastomosis on Short and long_term Clinical Outcome
试验速览
- 阶段
- 不适用
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Leakage rate
研究概览
简要总结
Prokinetic drugs used to accelerate healing of intestinal anastomosis of urgent cases which not prepared preoperative by increase intestinal motility and gastric emptying and decrease postoperative adhesions They are many types of prokinetics as cholinergic agonists, dopamine antagonist, serotonergic agonists and macrolides Agents of prokinetics administered immediately post operation and at the time of hospitalization
详细描述
By evaluation the effect of prokinetic use versus non use after emergency intestinal intestinal anastomosis on short and long term clinical outcome It will be prospective cohort study which conducted in sohag university hospital Study will include patients presented with urgent anastomosis Inclusion criteria: all adults underwent emergency intestinal anastomosis Exclusion criteria: pediatrics, patients with comorbidities and patients with electively resection and anastomosis.
Primary goals are to detect effect of prokinetics on incidence of leakage rate Secondary outcomes include early bowel opening, enteral feeding, post operative pain, wound infection and adhesion formation rate.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •all adult patients
排除标准
- •pediatrics
- •patients associated with comorbidities
- •patients with electively resection and anastomosis
研究组 & 干预措施
Prokinetic use in accelerate healing of urgent intestinal anastomosis
Prikinetic agents administered immediately post operative and time of stay at hospital twice daily
干预措施: Prokinetic Motility Agents as primpiram and gastreg (Drug)
结局指标
主要结局
Leakage rate
时间窗: 5 days postoperative
Fecal fistula
次要结局
- Early bowel opening(3 days postoperative)
研究者
Doha Adel Noureldin
Resident doctor at general surgery department sohag university hospital
Sohag University