Remote Ischemic Preconditioning Before Abdominal Surgery

Not Applicable

Withdrawn

• Conditions: Perioperative/Postoperative Complications
• Interventions: Procedure: Control; Procedure: Remote Ischemic Pre-conditioning

• Registration Number: NCT01340742
• Lead Sponsor: Lawson Health Research Institute

Brief Summary

Major abdominal surgeries are associated with perioperative cardiac morbidity of up to 10%.

Ischemic preconditioning may have a protective effect. The purpose of this study is to find out remote ischemic conditioning by inflating a blood pressure cuff on the arm will have a protective effect.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06
• Study First Submitted: 2011-02-14
• Study First Submitted QC: 2011-04-21
• Study First Posted: 2011-04-25
• Primary Completion: 2012-12
• Study Completion: 2013-06
• Status Verified: 2023-10
• Last Update Submitted: 2023-10-04
• Last Update Posted: 2023-10-06

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients undergoing abdominal surgery:large bowel, pancreatic and hepatic surgery

Exclusion Criteria

• Chronic inflammatory disease.
• Glyburide use before surgery.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
2	Control	Control group.
1	Remote Ischemic Pre-conditioning	Arm remote preconditioning

Primary Outcome Measures

Name	Time	Method
Cardiovascular Events: incidence of MI, TIA/stroke, death in both groups	One week

Secondary Outcome Measures

Name	Time	Method
Renal function deterioration in the first week after surgery	One week	Baseline Creatinine levels will be compared to the highest creatinine levels noted in the first 7 days of hospitalization

Trial Locations

Locations (1)

London Health Sciences Centre; 🇨🇦 London, Ontario, Canada