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Remote Ischemic Preconditioning Before Abdominal Surgery

Not Applicable
Withdrawn
Conditions
Perioperative/Postoperative Complications
Registration Number
NCT01340742
Lead Sponsor
Lawson Health Research Institute
Brief Summary

Major abdominal surgeries are associated with perioperative cardiac morbidity of up to 10%.

Ischemic preconditioning may have a protective effect. The purpose of this study is to find out remote ischemic conditioning by inflating a blood pressure cuff on the arm will have a protective effect.

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Patients undergoing abdominal surgery:large bowel, pancreatic and hepatic surgery
Exclusion Criteria
  • Chronic inflammatory disease.
  • Glyburide use before surgery.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Cardiovascular Events: incidence of MI, TIA/stroke, death in both groupsOne week
Secondary Outcome Measures
NameTimeMethod
Renal function deterioration in the first week after surgeryOne week

Baseline Creatinine levels will be compared to the highest creatinine levels noted in the first 7 days of hospitalization

Trial Locations

Locations (1)

London Health Sciences Centre

🇨🇦

London, Ontario, Canada

London Health Sciences Centre
🇨🇦London, Ontario, Canada

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