IRCT20190202042583N2已完成3 期
The effect of glutamine mouthwash in prevention of mucositis following the administration of high doses of methotrexate in children with acute lymphoblastic leukemia
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 5 years 至 10 years（—）
- 性别
- All
入选标准
- •Age of 5 to 10 years
- •ALL under the treatment of COG chemotherapy protocol
- •high dose of methotrexate
- •no mucositis before receiving methotrexate
- •no nausea and vomiting before starting methotrexate
- •platelet count above 100,000 per µl before From the onset of methotrexate
- •the absolute neutrophil count exceeds 1500 ml / µl before starting methotrexate
- •hemoglobin above 8 g / l
- •before starting methotrexate, the ability to use mouthwash for 30 seconds every 8 hours
- •Absence of mucositis at the initial visit
排除标准
- •presence of fever
- •use of systemic or topical antibiotics
研究者
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