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Clinical Trials/CTRI/2025/11/097977
CTRI/2025/11/097977
Not yet recruiting
Not Applicable

Comparative evaluation of effects of low- level laser therapy and low intensity pulsed ultrasound therapy on peri-implant bone density and soft tissue healing following dental implant surgery-A clinico radiographic study

Anju C1 site in 1 country30 target enrollmentStarted: January 19, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Anju C
Enrollment
30
Locations
1
Primary Endpoint
increase in peri implant bone density around the implant in low intensity pulsed ultrasound group

Overview

Brief Summary

1.Rationale

Dental implants are highly successful due to osseointegration. Peri implant soft tissue healing protects long term implant health. To enhance healing, low level laser therapy and low intensity pulsed ultrasound therapy offer non invasive options. Low level laser therapy  of 500 to 1200nm light stimulates angiogenesis, and osteoblastic function thereby accelerating bone remodelling and implant stability. Low intensity pulsed ultrasound therapy of 30 to 100 mw per centimeter square activates mechanotransduction, increasing growth factors and osteogenic genes .So adjuctive methods like LLLT and LIPUS  can improve bone regeneration and implant stabilty.

2 .Objective

To evaluate and compare effect of LLLT and LIPUS on peri implant bone density and soft tissue healing.

  1. Method

Implant placement will be done under local anesthesia. Sites will be randomly assigned into 3 groups. Group A  will be control group .Group B will be LLLT group with 940nm,100mW,356mW Per centimetersuare.Application will be immediately,3,7and 14 days after implant placement and 10 seconds per session.Group c will be LIPUS group with 1 MHZ,20mW and 100 mW per centimetersquare.Application will be 15 minute per session and twice weekely of 8 sessions.Follow up will be done after 3 months to assess peri implant bone density and soft tissue healing.Bone density will be assessed by CBCT in SIDEXIS software version 2.0.Soft tissue healing will be assessed by Langer’s healing index.

  1. Expected outcome

Peri implant bone density will be increased in LIPUS group and soft tissue healing will be increased in LLLT group.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 45.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • 1.Patients aged between 18 and 45 years, irrespective of gender 2.Presence of a single edentulous site in the posterior maxilla or mandible 3.Good oral hygiene and healthy adjacent teeth 4.Willingness to provide informed consent and adhere to study protocol.

Exclusion Criteria

  • 1.Systemic conditions contraindicating implant placement (e.g., uncontrolled diabetes, immunocompromised status) 2.History of radiotherapy or any medications that may alter bone density 3.Smokers and tobacco users 4.Pregnant or lactating women 5.Patients with poor oral hygiene or untreated periodontal disease.

Outcomes

Primary Outcomes

increase in peri implant bone density around the implant in low intensity pulsed ultrasound group

Time Frame: peri implant bone density will be assessed immediately after placement and 3 months.

Secondary Outcomes

  • improvement in soft tissue healing around the implants in the low level laser therapy group(soft tissue healing will be checked immediately, and 3, 7, and 14 consecutive days.)

Investigators

Sponsor
Anju C
Sponsor Class
Other []
Responsible Party
Principal Investigator
Principal Investigator

Anju C

Coorg Institute Of Dental Science

Study Sites (1)

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