Comparative evaluation of effects of low- level laser therapy and low intensity pulsed ultrasound therapy on peri-implant bone density and soft tissue healing following dental implant surgery-A clinico radiographic study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- increase in peri implant bone density around the implant in low intensity pulsed ultrasound group
研究概览
简要总结
1.Rationale
Dental implants are highly successful due to osseointegration. Peri implant soft tissue healing protects long term implant health. To enhance healing, low level laser therapy and low intensity pulsed ultrasound therapy offer non invasive options. Low level laser therapy of 500 to 1200nm light stimulates angiogenesis, and osteoblastic function thereby accelerating bone remodelling and implant stability. Low intensity pulsed ultrasound therapy of 30 to 100 mw per centimeter square activates mechanotransduction, increasing growth factors and osteogenic genes .So adjuctive methods like LLLT and LIPUS can improve bone regeneration and implant stabilty.
2 .Objective
To evaluate and compare effect of LLLT and LIPUS on peri implant bone density and soft tissue healing.
- Method
Implant placement will be done under local anesthesia. Sites will be randomly assigned into 3 groups. Group A will be control group .Group B will be LLLT group with 940nm,100mW,356mW Per centimetersuare.Application will be immediately,3,7and 14 days after implant placement and 10 seconds per session.Group c will be LIPUS group with 1 MHZ,20mW and 100 mW per centimetersquare.Application will be 15 minute per session and twice weekely of 8 sessions.Follow up will be done after 3 months to assess peri implant bone density and soft tissue healing.Bone density will be assessed by CBCT in SIDEXIS software version 2.0.Soft tissue healing will be assessed by Langer’s healing index.
- Expected outcome
Peri implant bone density will be increased in LIPUS group and soft tissue healing will be increased in LLLT group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients aged between 18 and 45 years, irrespective of gender 2.Presence of a single edentulous site in the posterior maxilla or mandible 3.Good oral hygiene and healthy adjacent teeth 4.Willingness to provide informed consent and adhere to study protocol.
排除标准
- •1.Systemic conditions contraindicating implant placement (e.g., uncontrolled diabetes, immunocompromised status) 2.History of radiotherapy or any medications that may alter bone density 3.Smokers and tobacco users 4.Pregnant or lactating women 5.Patients with poor oral hygiene or untreated periodontal disease.
结局指标
主要结局
increase in peri implant bone density around the implant in low intensity pulsed ultrasound group
时间窗: peri implant bone density will be assessed immediately after placement and 3 months.
次要结局
- improvement in soft tissue healing around the implants in the low level laser therapy group(soft tissue healing will be checked immediately, and 3, 7, and 14 consecutive days.)
研究者
Anju C
Coorg Institute Of Dental Science