Comparison of Heparin and Clexane in Thrombosis Prevention after Craniotomy
Phase 2
- Conditions
- Deep Vein Thrombosis.Phlebitis and Thrombophlebitis of other Deep Vessels of Lower ExtremitiesI 80.2
- Registration Number
- IRCT2012102711274N1
- Lead Sponsor
- Vice Chancellor for Research, University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 154
Inclusion Criteria
Inclusion criteria : Patients candidate for elective craniotomy due to brain tumor were enrolled in this randomized, double – blinded, controlled clinical trial from 2009 to 2010 in Isfahan IRAN.
exclusion criteria : Patients with bleeding into the primary lesion; history of thrombotic events in the post 6 moths; or recent anticoagulation use were excluded.
Patients that due to Paresis or plegia weren't ambulated even though treatment continued, excluded from our study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Deep Vein Thrombosis. Timepoint: Before intervention , After intervention daily (from 48 h after operation) until 7 days. Method of measurement: 1)Questionnaire, 2)Physical Examination 3) if any doubt remained Doppler Sonography was used.
- Secondary Outcome Measures
Name Time Method Blood Hypertention. Timepoint: Daily Physical Exams. Method of measurement: Daily physical exam.;Smoking history. Timepoint: Before intervention. Method of measurement: Questionnaire.;Diabetes Mellitus. Timepoint: Daily Physical Exams. Method of measurement: Lab Data.;Trombocytopenia. Timepoint: Daily. Method of measurement: Lab Data.