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临床试验/CTRI/2021/07/035031
CTRI/2021/07/035031已完成2 期

Analysis of neuromuscular physiological changes in type II diabetic mellitus clients following medium frequency electrical stimulation.

Riyas Basheer K B4 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2021年7月29日最近更新:

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
72
试验地点
4
主要终点
Muscle Strength by using Hand Held Dynamometer

研究概览

简要总结

Sensory symptoms and deficits are frequently observed in diabetic polyneuropathy, but motor deficits are more difficult to recognize or often neglected. As a part of a rehabilitation team, we observed altered muscle strength in T2DM in relation to neuropathy. This study was conducted to find the relationship of muscle strength in diabetes, subjects were characterized by microvascular complications and biochemical measurements. By using standard laboratory methods, biochemical measurements were taken, which included Fasting Blood Sugar level, HbA1c, Serum Creatine, Serum Insulin, C-peptide & Albumin excretion rate. The retinal status of the diabetic subjects was classified as normal, non-proliferative and proliferative retinopathy, renal status classified as incipient & overt nephropathy, and neuropathy as asymptomatic & symptomatic by ophthalmologist, nephrologist & neurologist respectively.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Participant, Investigator and Outcome Assessor Blinded

入排标准

年龄范围
30.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Type 2 DM Presence of microvascular complications.

排除标准

  • Diabetes other than Type 2 Stroke or other diseases that reducing the muscle strength Psychologically unstable individuals Not willing for consent Recent injuries to upper and lower limb.

结局指标

主要结局

Muscle Strength by using Hand Held Dynamometer

时间窗: at Baseline

次要结局

  • Serum Creatine(1.3 mg/dL)
  • FBS(99 mg/dL)
  • HbA1c(6%)
  • C-peptide(0.5 - 2.0 ng/mL)
  • Albumin Excretion Rate(30 mg/24Hrs)

研究者

发起方
Riyas Basheer K B
申办方类型
Other [self]

研究点 (4)

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