Role of new parameter by renal doppler study to predict onset of acute kidney injury in patients who have developed sepsis.
Not Applicable
- Conditions
- Health Condition 1: N178- Other acute kidney failure
- Registration Number
- CTRI/2021/09/036391
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1All 18-65 years old patients admitted in AIIMS with sepsis during study duration who will give consent for the study
2Feasibility of Renal doppler examinations within first 12 hours of admission.
3Sepsis defined as by Sepsis 3 criteria
Exclusion Criteria
1Poor abdominal echogenicity
2Chronic kidney disease
3AKI on admission
4Unilateral nephrectomy
5Renal transplant patients
6Unilateral or bilateral hydronephrosis
7Pregnant
8Renal tumor
9Suspected intra abdominal hypertension.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary objective <br/ ><br> The goals of this study are to determine the relationship between the renal doppler parameters calculated during first 12 hours of ICU admission and MAKE-30 (Major Adverse Kidney Events within 30 days) in septic patients admitted to the general ICU. <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: Primary objective <br/ ><br> The goals of this study are to determine the relationship between the renal doppler parameters calculated during first 12 hours of ICU admission and MAKE-30 (Major Adverse Kidney Events within 30 days) in septic patients admitted to the general ICU. <br/ ><br> <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method <br/ ><br>Secondary objectives <br/ ><br>To identify if these parameters can predict <br/ ><br>Development of AKI-3 <br/ ><br>Increased requirement of renal replacement therapy <br/ ><br>Increased ICU stay <br/ ><br>Need for mechanical ventilation and <br/ ><br>Increased mortality at 30days <br/ ><br>Timepoint: 30 Days from onset, discharge or death