Effect of oropharyngeal milk administration on the oral and gut microbiota of very low birth weight infant: Randomized controlled trial

Not Applicable

Completed

• Conditions: Gastrointestinal Microbiome; Microbiota; Oral immune therapy; Oropharyngeal milk; Very low birth weight infant; Preterm infant Oral care Microbiota

• Registration Number: TCTR20180306002
• Lead Sponsor: Targeted Research Grants, Faculty of Medicine, Prince of Songkla University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-03-06
• Study Completion: 2019-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

-Very low birth weight neonate (birth weight less than 1,500 grams)
-Inborn neonate

Exclusion Criteria

-Maternal death
-Contraindication of breast milk eg maternal HIV infection
-Gut anomalies
-Chromosome abnormality or moribund

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oral and gut microbiota Oral feed (oral) or 28 days of life (gut) NextGen

Secondary Outcome Measures

Name	Time	Method
Clinical outcomes until death or discharge record form