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A pharmacokinetic study of BBI-4000 gel in patients with primary focal hyperhidrosis in Japa

Phase 1
Conditions
Primary focal hyperhidrosis
Registration Number
JPRN-jRCT2071210041
Lead Sponsor
Yonemura Takuma
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
24
Inclusion Criteria

1. Aged >=20 and <65 years at the time of consent
2. BMI >=18.0 and <30.0 at screening
3. Diagnosed as having primary focal hyperhidrosis in the screening interview
4. Hyperhidrosis disease severity scale (HDSS) of 3 or 4 at screening

Exclusion Criteria

1. Secondary hyperhidrosis
2. Whose hyperhidrosis symptoms started or worsened due to menopause
3. Indicated forthoracic sympathectomy
4. Identified with findings other than hyperhidrosis at or near the site of study drug administration on the day of admission at baseline
5. Diagnosed by the investigator /sub-investigator with a complication that can disrupt normal sweat production
6. Diagnosed by the investigator /sub-investigator with glaucoma, prostatic hypertrophy, or any other complications that can be exacerbated by using of anticholinergics.
7. Complicated with hyperallergic to anticholinergics or topical agents, or history thereof

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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