aser effect in preventing the incidence of chemotherapy-induced oral ulcers in patients with acute leukemia

Not Applicable

• Conditions: Condition 1: acute lymphoblastic leukemia. Condition 2: acute myeloid leukemia.; Acute lymphoblastic leukaemia; Acute myelblastic leukaemia

• Registration Number: IRCT201110157801N1
• Lead Sponsor: Dental faculty, Shiraz university of medical sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

12-70 y/o; both genders; suffering acute myeloid/lymphoblastic leukemia; receiving myeloablative chemotherapy regimen; healthy oral mucosa at before starting chemotherapy; able to cooperation; filling the informed consent form. Exclusion criteria: unhealthy oral mucosa (erythema, ulcer, soreness) before starting chemotherapy; non ablative chemotherapy regimen; inability or unwillingness for being involved.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reducing the incidence of ulcer and erythema. Timepoint: 1 week, 2 weeks, 3 weeks, 4 weeks. Method of measurement: observation of the erythema and ulcer accordig to WHO & NCI scale.

Secondary Outcome Measures

Name	Time	Method
Reducing pain. Timepoint: 1 week, 2 weeks, 3 weeks, 4 weeks. Method of measurement: explaining the amount of pain according to the patients' expression (1-10 numbers).