Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Burnout Syndrome

Not Applicable

Completed

• Conditions: Burnout Syndrome; Interleukin-10; Neutrophil-Lymphocyte Ratio; Interleukin-6
• Interventions: Other: music therapy

• Registration Number: NCT05750160
• Lead Sponsor: Indonesia University

Brief Summary

Burnout Syndrome (BOS) can be defined as a state of stress both physically and psychically due to the burden and stressor of high work. The prevalence of BOS in health workers varies between 25-75% globally. Studies have shown that the presence of Burnout syndrome will meaningfully reduce the quality of services related to patient safety and cause immune system disorders that act as the body's defense against viral, bacterial, protozoal and fungal infections. Many strategies have been researched to help prevent and reduce the occurrence of Burnout syndrome, one of which is music therapy. The purpose of this study was to determine the effect of music therapy on the immune response in health workers with Burnout Syndrome.

This study is a randomized clinical trial with a pre and post test control group design for health workers at Dr Kariadi General Hospital and Dr. Cipto Mangunkusumo General Hospital. Subjects will be provided with information prior to the study and asked to sign an informed consent sheet if they agree to be involved in the study. Subjects will be divided into control groups and treatment groups with matching age, gender and type of work. In the treatment group, music therapy will be given as much as 3 times a week for 4 weeks. Data were taken on both groups before and after the intervention. This study used the Maslach Burnout Inventory Human Service Survey (MBI-HSS) and blood laboratory examination to determine the value of the Neutrophyl Lymphocyte Ratio, Interleukin 6 and Interleukin 10 levels.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-01-15
• Study Start: 2023-02-13
• Primary Completion: 2023-02-18
• Study First Submitted QC: 2023-02-20
• Study First Posted: 2023-03-01
• Study Completion: 2023-03-18
• Status Verified: 2023-06
• Last Update Submitted: 2023-06-01
• Last Update Posted: 2023-06-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Age 18 years - 60 years old
2. Health workers in the wards and polyclinic of Dr. Cipto Mangunkusumo Hospital or Dr. Kariadi Hospital, including doctors in charge of patients, nurses, residents, and other supporting health workers
3. Included in the Burnout syndrome criteria from the Maslach Burnout Inventory-Human Service Survey questionnaire

Exclusion Criteria

1. Refusing to follow the study
2. Have a history of heart disease, kidney disease, diabetes, cancer, tuberkulosis, autoimmune, immunodeficiency
3. Taking drugs that affect the central nervous system or immunosuppressants
4. Have hearing disorder
5. Have a psychiatric disorder
6. Being pregnant
7. Healthcare workers who don't like music

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention	music therapy	Given education and music therapy

Primary Outcome Measures

Name	Time	Method
Neutrophil Lymphocyte Ratio	Change from baseline Neutrophil Lymphocyte Ratio at 4 weeks	Measured with Fluorescence Flow Cytometry
Interleukin 6	Change from baseline Interleukin-6 level at 4 weeks	Measured with Fluorescence Immunoassay
Interleukin 10	Change from baseline Interleukin-10 level at 4 weeks	Measured with ELISA
Burnout syndrome	change from baseline score at 4 weeks	Maslach Burnout Inventory Human Service Survey (MBI-HSS) score

Trial Locations

Locations (1)

Cipto Mangunkusumo National Hospital; 🇮🇩 Jakarta, Indonesia