PS Poisonings reported to four European Poison Control Centers in 2021

Recruiting

Conditions: T65.9
Toxic effect of unspecified substance

Registration Number: DRKS00031995

Lead Sponsor: Vergiftungs-Informations-Zentrale, Allgemeinpädiatrie, Zentrum für Kinder- und Jugendmedizin, Universitätsklinikum Freiburg, Medizinische Fakultät - Albert-Ludigs-Universtität, Freiburg

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 50

Inclusion Criteria

To be included in this study, a case must meet all of the following criteria:
-a patient with at least one reported exposure to a NPS for who a call is made to one of the participating PCCs.
-The following cases are included:
oCases for who calls were made by the general public and by medical professionals.
oCases of all ages and gender.
oCases with and without concomitant exposure.
oCases with and without symptoms.
oCases with acute, acute on chronic, and chronic NPS exposures.
oCases with withdrawal symptoms.
oCases with an NPS exposure, but for who the PCC was consulted on another exposure (e.g., a medication overdose).

Exclusion Criteria

A case who meets any of the following criteria will be excluded from inclusion in this study:
•All human patients without a reported NPS exposure for who a call is made to Danish, Dutch, Freiburg (Germany), or the Swiss PCC.
•The following cases are excluded:
oAll veterinary cases.
oCases with an exposure to unknown drugs (and not a specified NPS).
Cases with a NPS exposure that was not reported during one of the consultations with the PCC. For example, cases with a NPS exposure, based only on later exposure analysis.

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The main study parameter is the number of and the rate of (specific) NPS poisonings reported to the four PCCs in 2021. The NPS poisoning rate is calculated relative to common drug poisonings. The proportion of specific classes of NPS are also studied.

Secondary Outcome Measures

Name	Time	Method
Secondary study parameters are patient characteristics: <br>-age group, gender <br>- exposure characteristics: route of exposure, dose, type of exposure (acute/chronic), concomitant exposures. <br>- symptoms reported during PCC consultation: coma (EMV), convulsion, hyperthermia (temp C), tachycardia (HF/min), bradycardia (HF/min), hypertension (BP mmHg), hypotension (BP (mmHg)), tachypnea (rate/min), saturation, agitation, aggression.<br>- Differences between countries.