Prediction of Hypotension During Induction of General Anesthesia

• Conditions: Anesthesia

• Registration Number: NCT06078228
• Lead Sponsor: Ain Shams University

Brief Summary

Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents. Ultrasonographic measurement of the Carotid artery corrected flow time and internal jugular vein collapsibility index may predict post induction hypotension.

Detailed Description

* Type of Study: Observational Prospective Cohort Design.

* Study Setting and ethical consideration: The approval of the Scientific Research Ethics Committee of the Faculty of Medicine, Ain Shams University will be obtained before starting work on the study. This study will be conducted in operating theatres of Ain Shams University Hospitals. Informed written consents to participate will be obtained from the patients.

* Study Period: One year (October 2023-October 2024)

* Study Population: Adult patient undergoing elective surgeries.

Study Timeline

• Status Verified: 2023-09
• Study Start: 2023-09-24
• Study First Submitted: 2023-10-05
• Study First Submitted QC: 2023-10-05
• Study First Posted: 2023-10-11
• Last Update Submitted: 2024-08-02
• Last Update Posted: 2024-08-05
• Primary Completion: 2024-08-17
• Study Completion: 2024-08-17

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• 1- Patients of American Society of Anesthesiologists (ASA) physical status I to II of both genders.

  2- Aged 18-65 years. 3- Elective surgeries under general anesthesia. 4- BMI less than 40.

Exclusion Criteria

• Patients with

  1. Renal diseases.
  2. Hepatic diseases.
  3. ASA scores of 3-4.
  4. The presence of a left ventricular ejection fraction less than 50%.
  5. Age under 18 years old.
  6. Patient refusal.
  7. Coronary heart disease.
  8. Cardiac disease including cardiomyopathy and mild to severe valve disease.
  9. Pulmonary hypertension.
  10. Peripheral arterial disease.
  11. Preoperative cervical vascular ultrasound abnormalities including plaque, stenosis and anatomical variation.
  12. Any previous neck surgery or trauma.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the predictive value of the carotid Ftc for prediction of hypotension.	one year	to investigate the reliability of preanesthetic ultrasound measurements of the carotid artery FTc and the internal jugular vein collapsibility index in predicting hypotension during the induction of general anesthesia

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, Abbassia, Egypt