Examination on the effect of green tea catechin on improvement of digestive tract environment

Not Applicable

Recruiting

• Conditions: Healthy subjects

• Registration Number: JPRN-UMIN000042909
• Lead Sponsor: Kyoto Prefectural University of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-01-06
• Study Completion: 2022-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Not provided

Exclusion Criteria

1. Those who are treating diseases that affect the research results (dental and oral diseases, digestive diseases, etc.) 2. Those who have an extremely irregular diet 3. Those who drink a lot of green tea and alcohol on a daily basis 4. Those who habitually engage in strenuous exercise such as marathons 5. Currently, under the guidance of a doctor, those who are or will be doing exercise therapy / diet therapy 6. Serious heart disease [heart failure, myocardial infarction, myocarditis, etc.], liver disease [liver failure symptoms (fulminant hepatitis), liver cirrhosis, liver tumor], renal disease [nephrotic syndrome, renal failure (acute and chronic), urinary poisoning Disease, hydronephrotic syndrome], neurological disease, psychiatric disease, malignant tumor disease, etc., and those who have general condition problems 7. Those who have participated in other clinical trials within one month before obtaining consent or who plan to participate in other clinical trials during the trial period. 8. In addition, those who are judged by the investigator to be inappropriate for the study (the risk to the study subject may increase or sufficient data may not be obtained).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To analyze the change of oral bacteria and fecal bacteria before and after catechin intake by 16S rRNA metagenomic analysis by Illumina Miseq.

Secondary Outcome Measures

Name	Time	Method
Bile acids and short-chain fatty acids in the stool before and after ingestion, and urinary metabolites are measured before and after catechin intake as metabolites of intestinal bacteria.