Effect of Supplementation With 2000 International Units (IU) Vitamin D, 1gm Calcium or Both on Calcium Absorption and Bone Mineralization in Children With Juvenile Rheumatoid Arthritis
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Percent true calcium absorption
研究概览
简要总结
2000 international units (IU) vitamin D, 1 gram (gm) calcium, or both given to children with Juvenile Rheumatoid Arthritis (JRA) may increase percent true calcium absorption, bone mineral turnover and/or bone mineralization.
详细描述
Supplementation With 2000 IU Vitamin D, 1 gm Calcium or Both on Calcium Absorption and Bone Mineralization in Children With Juvenile Rheumatoid Arthritis may increase percent true calcium absorption, bone mineral turnover and/or bone mineralization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 3 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Juvenile Rheumatoid arthritis
排除标准
- •Steroid use
研究组 & 干预措施
Placebo
order of interventions placebo,calcium, cholecalciferol, calcium plus cholecalciferol
干预措施: Cholecalciferol (Dietary Supplement)
Placebo
order of interventions placebo,calcium, cholecalciferol, calcium plus cholecalciferol
干预措施: Calcium (Dietary Supplement)
Placebo
order of interventions placebo,calcium, cholecalciferol, calcium plus cholecalciferol
干预措施: Calcium and cholecalciferol (Dietary Supplement)
Placebo
order of interventions placebo,calcium, cholecalciferol, calcium plus cholecalciferol
干预措施: Placebo (Drug)
Calcium
order of treatment calcium, placebo, calcium plus cholecalciferol, cholecalciferol
干预措施: Cholecalciferol (Dietary Supplement)
Calcium
order of treatment calcium, placebo, calcium plus cholecalciferol, cholecalciferol
干预措施: Calcium (Dietary Supplement)
Calcium
order of treatment calcium, placebo, calcium plus cholecalciferol, cholecalciferol
干预措施: Calcium and cholecalciferol (Dietary Supplement)
Calcium
order of treatment calcium, placebo, calcium plus cholecalciferol, cholecalciferol
干预措施: Placebo (Drug)
Cholecalciferol
order of treatments cholecalciferol, calcium and Cholecalciferol, placebo, and calcium
干预措施: Cholecalciferol (Dietary Supplement)
Cholecalciferol
order of treatments cholecalciferol, calcium and Cholecalciferol, placebo, and calcium
干预措施: Calcium (Dietary Supplement)
Cholecalciferol
order of treatments cholecalciferol, calcium and Cholecalciferol, placebo, and calcium
干预措施: Calcium and cholecalciferol (Dietary Supplement)
Cholecalciferol
order of treatments cholecalciferol, calcium and Cholecalciferol, placebo, and calcium
干预措施: Placebo (Drug)
Calcium and cholecalciferol
order of treatment calcium and cholecalciferol, cholecalciferol, calcium, placebo
干预措施: Cholecalciferol (Dietary Supplement)
Calcium and cholecalciferol
order of treatment calcium and cholecalciferol, cholecalciferol, calcium, placebo
干预措施: Calcium (Dietary Supplement)
Calcium and cholecalciferol
order of treatment calcium and cholecalciferol, cholecalciferol, calcium, placebo
干预措施: Calcium and cholecalciferol (Dietary Supplement)
Calcium and cholecalciferol
order of treatment calcium and cholecalciferol, cholecalciferol, calcium, placebo
干预措施: Placebo (Drug)
结局指标
主要结局
Percent true calcium absorption
时间窗: After 6 months of treatment
次要结局
- Bone Mineralization by Dual Energy x-ray absorption(After 6 months treatment plus 3 month washout)