HERNIA-study: congenital diaphragmatic Hernia, Environment, Retinoids, Nutrition, Inheritance, other Associations

Completed

• Conditions: hernia; diaphragmatic defect; 10038686; 10028920

• Registration Number: NL-OMON29811
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Congenital Diaphragmatic Hernia in the (unborn) child

Exclusion Criteria

non-matching (controls; see protocol)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary study parameter is a significant difference in the levels of retinoids<br /><br>between mothers and children with CDH and healthy mothers/newborns.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- A difference in the genetic profile between patients and controls<br /><br>- Identification of a possible relationship between nutrional and environmental<br /><br>factors and the etiology of CDH</p><br>