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A clinical study to evaluate efficacy of a copper containing intrauterine device (Coated Copper- T) in reducing bleeding side effects.

Phase 2
Completed
Registration Number
CTRI/2016/01/006535
Lead Sponsor
HLL Lifecare Limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
176
Inclusion Criteria

1. Age between 21 and 35 years (inclusive),

2. In good general health

3. With proven fertility and requesting

contraception(Nulliparous women requesting

contraception can also be included)

4. Has regular menstrual cycles (length of cycle

21-35 days) (i.e., endogenous Cyclicity without

hormonal contraceptive use)

Exclusion Criteria

1.Known or suspected pregnancy

2.Breast feeding females

3.Patients using anti-coagulants

4.History of ectopic pregnancies

5.Any genital infection (until successfully treated)

6.Abnormal uterine bleeding of any origin including bleeding due to unknown causes

7.Abnormalities of the uterus resulting in distortion of the uterine cavity

8.Postpartum endometritis or infected abortion and MTP in the past < 3 months

9.Known or suspected uterine or cervical malignancy, including unresolved, abnormal â??Papâ?? smear

10.Untreated acute cervicitis until infection is controlled

11.Diagnosed Wilsonâ??s disease

12.Known allergy to copper

13.Conditions associated with increased susceptibility to infection. Such conditions include, but are not limited to leukemia, diabetes acquired immune deficiency syndrome (AIDS), and those requiring chronic corticosteroid therapies

14.Genital actinomycosis

15.A previously inserted IUD that has not been removed

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess heavy menstrual bleeding between two groups using coated Copper T and conventional Copper T device.Timepoint: 12 months
Secondary Outcome Measures
NameTimeMethod
IUD removals are detected during the scheduled visits. IUD must be removed from the subject at the end of the study.Timepoint: 12 months;Pain and comfort level will be assessed by the Quality of Life questionnaire.Timepoint: 12 months;patient reports IUD expulsion, these events are detected during the scheduled visitsTimepoint: 12 months;positive urine pregnancy test at any time within 12 months of the studyTimepoint: 12 months
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