Granisteron Versus Metoclopramide in Laparoscopic Cholecystectomy

Phase 4

• Conditions: Nausea and Vomiting, Postoperative
• Interventions: Drug: Granisetron

• Registration Number: NCT04899817
• Lead Sponsor: Assiut University

Brief Summary

Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy

Detailed Description

Post operative nausea and vomitting is Avery common complication of laparoscopic surgery in that study we will compare between granisteron and metoclopramide as aprophlaxis against post operative nausea and vomitting

Study Timeline

• Study First Submitted: 2021-04-20
• Status Verified: 2021-05
• Study Start: 2021-05
• Study First Submitted QC: 2021-05-19
• Last Update Submitted: 2021-05-19
• Study First Posted: 2021-05-25
• Last Update Posted: 2021-05-25
• Primary Completion: 2022-03
• Study Completion: 2022-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• both sexes Age between 18 and 60 years ASA1 2 3 Lap cholecystectomy under general anesthesia

Exclusion Criteria

• patients refusal Pregnancy and breastfeeding Hepatic or renal disease ASA4 5 Allergy to the drug

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group C	Granisetron	Will receive metoclopramide 10 mg after induction of general anesthesia
Group G	Granisetron	will receive granisteron 1mg after induction of general anesthesia

Primary Outcome Measures

Name	Time	Method
Postoperative nausea and vomitting	Every 2 hours for 12 hours	Number of attacks of nausea and vomitting

Trial Locations

Locations (1)

Assiut university hospital; 🇪🇬 Assiut, Egypt