Intraocular Pressure and Ocular Biometrics Changes After Phacoemulsification in Glaucomatous Patients and Age Matched Controls, Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 37
- 试验地点
- 2
- 主要终点
- ocular bio-metrics change
研究概览
简要总结
Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also been studied. In our study we aim at establishing a quantitative relationship between preoperative ocular biometrics and postoperative intraocular pressure change and comparing this relationship in glaucomatous and non-glaucomatous eyes.
详细描述
All patients will have the anterior chamber angle assessed by indentation gonioscopy preoperatively. Anterior Chamber Depth & lens thickness will be measured by Optical Biometry (lenstar 900) as well as measurement of the angle & lens vault using the Ultrasound Biomicrosopy (UBM) before and 1 month after cataract surgery. IOP will be measured pre- & postoperatively on day 7 and 30. Possible Risk (s): Risks of surgery(hemorrhage, endophthalmitis), Risks for investigations: minimal risk of infection To minimize the risk of infection: adherence to pre-& intraoperative infection-control measures, postoperative UBM is to be done at 1 month.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 40-70 years.
- •Glaucomtous and nonglaucomatous participants with visually significant cataracts.
- •Best-corrected visual acuity (BCVA) equal to or worse than 6/
- •patients candidates for standard cataract surgeries without adjunctive procedure (e.g., pupil stretching or iris hooks).
排除标准
- •Major intraoperative or postoperative complications from cataract surgery
- •Peripheral anterior synechiae (PAS) detected by indentation gonioscopy.
- •Uveitis, severe retinal diseases, or congenital Anomalies.
- •History of ocular trauma or any intraocular Surgery. ocular trauma or any intraocular Surgery
结局指标
主要结局
ocular bio-metrics change
时间窗: 4 weeks
anterior chamber angle angle opening distance and anterior chamber depth change
Intraocular pressure change
时间窗: 4 weeks
intraocular pressure measurement by Goldman's applanation tonometr
次要结局
- Phacoemulsification as treatment to glaucoma(4 weeks)
研究者
Mai Nasser Abd Elmohsen
Lecturer of ophthalmology
Kasr El Aini Hospital