Intraocular Pressure and Ocular Biometrics Changes After Phacoemulsification in Glaucomatous Patients and Age Matched Controls, Comparative Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Glaucoma
- Sponsor
- Mai Nasser Abd Elmohsen
- Enrollment
- 37
- Locations
- 1
- Primary Endpoint
- ocular bio-metrics change
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also been studied. In our study we aim at establishing a quantitative relationship between preoperative ocular biometrics and postoperative intraocular pressure change and comparing this relationship in glaucomatous and non-glaucomatous eyes.
Detailed Description
All patients will have the anterior chamber angle assessed by indentation gonioscopy preoperatively. Anterior Chamber Depth \& lens thickness will be measured by Optical Biometry (lenstar 900) as well as measurement of the angle \& lens vault using the Ultrasound Biomicrosopy (UBM) before and 1 month after cataract surgery. IOP will be measured pre- \& postoperatively on day 7 and 30. Possible Risk (s): Risks of surgery(hemorrhage, endophthalmitis), Risks for investigations: minimal risk of infection To minimize the risk of infection: adherence to pre-\& intraoperative infection-control measures, postoperative UBM is to be done at 1 month.
Investigators
Mai Nasser Abd Elmohsen
Lecturer of ophthalmology
Kasr El Aini Hospital
Eligibility Criteria
Inclusion Criteria
- •Age 40-70 years.
- •Glaucomtous and nonglaucomatous participants with visually significant cataracts.
- •Best-corrected visual acuity (BCVA) equal to or worse than 6/
- •patients candidates for standard cataract surgeries without adjunctive procedure (e.g., pupil stretching or iris hooks).
Exclusion Criteria
- •Major intraoperative or postoperative complications from cataract surgery
- •Peripheral anterior synechiae (PAS) detected by indentation gonioscopy.
- •Uveitis, severe retinal diseases, or congenital Anomalies.
- •History of ocular trauma or any intraocular Surgery. ocular trauma or any intraocular Surgery
Outcomes
Primary Outcomes
ocular bio-metrics change
Time Frame: 4 weeks
anterior chamber angle angle opening distance and anterior chamber depth change
Intraocular pressure change
Time Frame: 4 weeks
intraocular pressure measurement by Goldman's applanation tonometr
Secondary Outcomes
- Phacoemulsification as treatment to glaucoma(4 weeks)