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Standard treatment compared to intensified treatment with pegfilgrastim support in patients with small-cell lung cancer, limited disease. A phase III study. - The STING 2 study

Conditions
Small Cell Lung Cancer (limited disease)
Registration Number
EUCTR2006-005754-80-SE
Lead Sponsor
Karolinska University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
128
Inclusion Criteria

Histologically verified diagnosis of small cell lung cancer
Limited disease as stage I,II or III
Performance status <= 2
Leukocyte count (LPC) > 3 * 10(9)/L
Thrombocyte count (TPC) > 100*10(9)/L
ASAT/ALAT < 3 * normal value
Crreatinine < 1.5 * normal value
Age 18-75 years
Formerly untreated patients

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Serious heart disease, kidney disease, impaired lung function or other disease which may pose risk to standard treatment
Reduced ability to cooperate
Performance status 3 and 4
History of malignant disease other than basal cell carcinoma or stage I cancer of the cervix
Pregnant or breast feeding

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main Objective: 2 year survival;Secondary Objective: 5 year survival and overall survival as well as toxicity, frequency of CR and good PR;Primary end point(s): 2 year survival
Secondary Outcome Measures
NameTimeMethod
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