ExtraCorporeal Life Support (ECLS) Versus IMPELLA™ Pump as Bridge to Left Ventricular Assist Device
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiogenic Shock
- Sponsor
- University Hospital, Bordeaux
- Enrollment
- 92
- Locations
- 5
- Primary Endpoint
- Proportion of patients alive in the surgery ward, not requiring intravenous access and walking (John Hopkins highest level of mobility (JH-HLM) scale = 8 at 30 days after the LVAD implantation
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
In this retrospective observational multicenter study the authors tested the hypothesis that the use of IMPELLA™ pump as bridge to bridge, by giving the opportunity of active rehabilitation, should improve patient's outcomes after the implantation of Left Ventricular Assist Device (LVAD).
Detailed Description
End stage heart failure patients admitted in Intensive Care Unit (ICU) for refractory cardiogenic shock requiring short-term mechanical circulatory support as a bridge to a long-term LVAD might benefit from early mobilization and rehabilitation with IMPELLA™ inserted via the axillary artery. The aim of this study is to compare the early rehabilitation and outcomes after LVAD implantation between patients previously treated by IMPELLA™ or ExtraCorporeal Life Support (ECLS)
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients supported with IMPELLA™ or ECLS for refractory cardiogenic shock as a bridge to long duration LVAD
Exclusion Criteria
- •Patient refusing to give access to their medical chart
- •Guardianship and curactorship
- •Deprived of liberty
- •short term mechanical circulatory system weaned before LVAD implantation
Outcomes
Primary Outcomes
Proportion of patients alive in the surgery ward, not requiring intravenous access and walking (John Hopkins highest level of mobility (JH-HLM) scale = 8 at 30 days after the LVAD implantation
Time Frame: Day 30 after Left Ventricular Assist Device (LVAD) implantation
Proportion of patients alive in the surgery ward, not requiring intravenous access and walking (John Hopkins highest level of mobility (JH-HLM) scale = 8) at 30 days after the LVAD implantation
Secondary Outcomes
- Organ dysfunction before LVAD implantation(The day before LVAD implantation)
- SOFA score(Day 7 post LVAD implantation)
- length of stay(up to hospital discharge (not more than 6 months after LVAD implantation))
- Complication and rehabilitation under Short-term Mechanical Circulatory support(The day of Left Ventricular Assist Device (LVAD) implantation)
- complication Under LVAD(The day of Intensive Care Unit (ICU) discharge)
- Vital status(6 months after LVAD implantation)