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Clinical Trials/NCT06093789
NCT06093789
Completed
N/A

The Relationship Between Personality Traits and Perioperative Anesthetic Drug Consumption

Ondokuz Mayıs University1 site in 1 country90 target enrollmentNovember 1, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Anesthesia
Sponsor
Ondokuz Mayıs University
Enrollment
90
Locations
1
Primary Endpoint
Propofol consumption
Status
Completed
Last Updated
last year

Overview

Brief Summary

In this study, we aimed to examine the association between personality traits and amount of anesthetic drug consumption,of the patients who will receive sedoanalgesia for the oocyte retrieval procedure. As well as determining the anxiety scores in the preoperative period, the time to reach the desired sedation level, hemodynamic parameters in the perioperative period, peripheral oxygen saturation, EtCO2 value, postoperative pain, postanesthetic recovery, analgesic drug need, unconscious movement, and patient satisfaction.

Detailed Description

Different personality traits, anxiety disorders, depression, and somatoform disorders are frequently encountered in women with infertility problems. Although there are many studies evaluating the relationship of anxiety with variables such as hemodynamic parameters, need for anesthetic medication, recovery times, postoperative pain and analgesic requirements, the relationship between personality traits and these variables has not been investigated. In our study, considering that the anesthesia needs of these patients with a stressful negative factor such as infertility may be at different levels, preoperative evaluation of the patients with a personality questionnaire will provide better perioperative management, a better quality recovery and possibly a higher quality oocyte aspiration. In this study, it was aimed to investigate the amount of anesthetic agent consumption, recovery times, postoperative pain scores, analgesic requirements, involuntary movement, time to reach sufficient sedation depth, and patient satisfaction of patients thought to have sedation. All patients will fill out Personality Belief Scale-Short Form (PBQ-S1) and Beck Anxiety Scale one day before the procedure and they will be registered.

Registry
clinicaltrials.gov
Start Date
November 1, 2023
End Date
July 30, 2024
Last Updated
last year
Study Type
Observational
Sex
Female

Investigators

Sponsor
Ondokuz Mayıs University
Responsible Party
Principal Investigator
Principal Investigator

SEZGİN BİLGİN

MD

Ondokuz Mayıs University

Eligibility Criteria

Inclusion Criteria

  • 18- 50 year-old elective patients who signed the informed consent form from ASA I-II patients scheduled for oocyte retrieval.
  • Patients with sufficient education and mental capacity to complete in assessment scales and questionnaires.
  • Patients without neurological disorders, psychological illnesses, or drug or alcohol abuse
  • Patients without stimulant drug and alcohol consumption
  • Absence of significant cardiovascular, respiratory, kidney or liver disease.

Exclusion Criteria

  • Psychiatric or neurological disorder
  • Psychiatric drug use or alcohol consumption
  • Pregnancy
  • Presence of severe cardiac, hepatic or cerebrovascular disease
  • History of allergy to local anesthetics or systemic opioids
  • History of chronic pain
  • Patients who are unable to evaluate scales and questionnaires

Outcomes

Primary Outcomes

Propofol consumption

Time Frame: from the beginning to the end of the transvaginal oocyte retrieval procedure)

mg, from the beginning to the end of the transvaginal oocyte retrieval procedure

Secondary Outcomes

  • Amount of propofol (mg) used until the required sedation depth is reached(The period of time starting with the propofol injection until the Ramsey Sedation Score of 4)
  • Peripheral oxygen saturation (%)(every 5 minutes during the procedure)
  • Number of Involuntary movement during the procedure(during the procedure.)
  • Postoperative pain (visual analog scale)(After the procedure,every 30 minutes up to 1 hour)
  • Heart rate (beats/min)(every 5 minutes during the procedure.)
  • Time until the Ramsey Sedation Score of 4 is reached(-The period of time starting with the propofol injection until the Ramsey Sedation Score of 4)
  • Systolic, diastolic and, mean Blood pressure (mm/Hg)(every 5 minutes during the procedure)
  • Analgesic consumption(postoperatively up to 2 hours)
  • Postoperative recovery time(postoperatively up to 2 hours)
  • The incidences of post-operative nausea and vomiting (PONV)(the time from the end of the procedure until discharge)
  • Undesirable events and interventions(time between start of procedure and discharge)

Study Sites (1)

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