Evaluating the Use of a Device Called Impulse Oscillometry in Participants With Vocal Cord Disorders or Asthma

Completed

• Conditions: Asthma; Lung Function Decreased; Vocal Cord Dysfunction; Laryngeal Obstruction; Breathing, Mouth
• Interventions: Device: Impulse Oscillometer

• Registration Number: NCT05246930
• Lead Sponsor: University of Rochester

Brief Summary

This study will determine if airway resistance to airflow and pressure, measured by Impulse Oscillometry, is impacted in subjects with vocal cord disorders and whether these measurements are different when compared to subjects with asthma.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-02-08
• Study First Submitted QC: 2022-02-08
• Study First Posted: 2022-02-18
• Study Start: 2022-06-15
• Primary Completion: 2024-06-01
• Status Verified: 2024-12
• Study Completion: 2024-12-01
• Last Update Submitted: 2024-12-13
• Last Update Posted: 2024-12-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 43

Inclusion Criteria

• Vaccinated against COVID-19 or testing negative for COVID-19 by viral PCT within 5 days before testing
• Willingness to perform breathing test
• Must be able to speak and understand English
• Documented diagnosis of asthma, documented clinical diagnosis of vocal cord dysfunction, or undergoing evaluation for vocal cord dysfunction

Exclusion Criteria

• Unable to provide consent or perform oscillometry test

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Subjects with diagnosis of asthma	Impulse Oscillometer	Subjects with physician-diagnosed asthma. Some subjects will have concomitant diagnosis of vocal cord dysfunction.
Subjects with a diagnosis of vocal cord dysfunction	Impulse Oscillometer	Subjects with a confirmed or suspected diagnosis of vocal cord dysfunction (also called inducible laryngeal obstruction). Some subjects will have concomitant diagnosis of asthma.

Primary Outcome Measures

Name	Time	Method
Mean respiratory system impedance	Single measurement, approximately day 1	The oscillometer will collect an airway impedance measurement which is made up of multiple variables.

Trial Locations

Locations (1)

Mary Parkes Asthma and Allergy Center; 🇺🇸 Rochester, New York, United States