Ultrasonographic and MRI Explorations of Infraspinatus Muscle in Postero-superior Rotator Cuff Tear
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3
- 试验地点
- 1
- 主要终点
- MRI Texture Index (MTI)
研究概览
简要总结
The project aims to evaluate the contribution of texture analysis on MRI sections, and the technical feasibility, reproducibility, and clinical relevance of quantitative ultrasound and elastography to characterize the composition and volume of infraspinatus muscle in postero-superior rotator cuff tears. The perspectives are to optimize the imaging to allow a quantitative, objective and reproducible analysis of the muscle tissue and its characteristics.
详细描述
The rotator cuff of the shoulder consists of 4 tendinomuscular units including the infraspinatus. This complex system fulfils a double role: stabilization/coaptation (raising the arm) and arm mobility (especially external rotation). Rupture of rotator cuff tendons is frequent (> 80% among chronic shoulder pain). They go with a decrease in muscle volume (amyotrophy) and irreversible fat infiltration. The treatment is medical and then surgical (if necessary). The degrees of atrophy and muscle infiltration (especially infraspinatus) are the criteria of choice for surgery. Actually, they are assessed in MRI according to the classification of Fuchs; it is operator dependent, qualitative and poorly reproducible with a strong inter-observer variability. Our team highlighted (2016) the possibility of using texture analysis software to objectively measure the proportion of fatty tissue on MRI sections of the cuff rotator muscles. This work also showed the possibility of using mode B ultrasound for morphological imaging and shear wave elastography to estimate the elasticity of the infraspinatus. The project aims to evaluate the contribution of texture analysis on MRI sections, and the technical feasibility, reproducibility, and clinical relevance of quantitative ultrasound and elastography to characterize the composition and volume of infraspinatus muscle in postero-superior rotator cuff tears. The perspectives are to optimize the imaging to allow a quantitative, objective and reproducible analysis of the muscle tissue and its characteristics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 35 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 35 years-old and ≤75 years-old
- •tendonous, transfixing, postero-superior, unilateral and symptomatic rotator cuff lesions
- •controlateral shoulder without symptom, without rotator cuff injuries, without medical ou surgical history
- •written informed consent
- •affiliation to a social security system
排除标准
- •pregnant woman
- •patient under legal protection
- •contraindications to MRI
- •traumatic or surgical or medical relevant history on shoulder
- •general or local disease affecting the skeletal striated muscle
研究组 & 干预措施
Postero-superior Rotator Cuff Tear
MRI, ultrasonographic explorations
干预措施: MRI (Other)
Postero-superior Rotator Cuff Tear
MRI, ultrasonographic explorations
干预措施: ultrasonographic explorations (Other)
Healthy Postero-superior Rotator Cuff
MRI, ultrasonographic explorations
干预措施: MRI (Other)
Healthy Postero-superior Rotator Cuff
MRI, ultrasonographic explorations
干预措施: ultrasonographic explorations (Other)
结局指标
主要结局
MRI Texture Index (MTI)
时间窗: up to 2 months
MRI texture index (MTI) on the healthy side and pathological side
次要结局
- velocity of shear wave in m.s-1(up to 2 months)
- Ultrasound Texture Index (UTI)(up to 2 months)
