Ultrasonographic and MRI Explorations of Infraspinatus Muscle in Postero-superior Rotator Cuff Tear
- Conditions
- Rotator Cuff Tears
- Interventions
- Other: MRIOther: ultrasonographic explorations
- Registration Number
- NCT04223440
- Lead Sponsor
- University Hospital, Tours
- Brief Summary
The project aims to evaluate the contribution of texture analysis on MRI sections, and the technical feasibility, reproducibility, and clinical relevance of quantitative ultrasound and elastography to characterize the composition and volume of infraspinatus muscle in postero-superior rotator cuff tears. The perspectives are to optimize the imaging to allow a quantitative, objective and reproducible analysis of the muscle tissue and its characteristics.
- Detailed Description
The rotator cuff of the shoulder consists of 4 tendinomuscular units including the infraspinatus. This complex system fulfils a double role: stabilization/coaptation (raising the arm) and arm mobility (especially external rotation). Rupture of rotator cuff tendons is frequent (\> 80% among chronic shoulder pain). They go with a decrease in muscle volume (amyotrophy) and irreversible fat infiltration. The treatment is medical and then surgical (if necessary). The degrees of atrophy and muscle infiltration (especially infraspinatus) are the criteria of choice for surgery. Actually, they are assessed in MRI according to the classification of Fuchs; it is operator dependent, qualitative and poorly reproducible with a strong inter-observer variability. Our team highlighted (2016) the possibility of using texture analysis software to objectively measure the proportion of fatty tissue on MRI sections of the cuff rotator muscles. This work also showed the possibility of using mode B ultrasound for morphological imaging and shear wave elastography to estimate the elasticity of the infraspinatus. The project aims to evaluate the contribution of texture analysis on MRI sections, and the technical feasibility, reproducibility, and clinical relevance of quantitative ultrasound and elastography to characterize the composition and volume of infraspinatus muscle in postero-superior rotator cuff tears. The perspectives are to optimize the imaging to allow a quantitative, objective and reproducible analysis of the muscle tissue and its characteristics.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 30
- ≥ 35 years-old and ≤75 years-old
- tendonous, transfixing, postero-superior, unilateral and symptomatic rotator cuff lesions
- controlateral shoulder without symptom, without rotator cuff injuries, without medical ou surgical history
- written informed consent
- affiliation to a social security system
- pregnant woman
- patient under legal protection
- contraindications to MRI
- traumatic or surgical or medical relevant history on shoulder
- general or local disease affecting the skeletal striated muscle
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Postero-superior Rotator Cuff Tear MRI MRI, ultrasonographic explorations Postero-superior Rotator Cuff Tear ultrasonographic explorations MRI, ultrasonographic explorations Healthy Postero-superior Rotator Cuff MRI MRI, ultrasonographic explorations Healthy Postero-superior Rotator Cuff ultrasonographic explorations MRI, ultrasonographic explorations
- Primary Outcome Measures
Name Time Method MRI Texture Index (MTI) up to 2 months MRI texture index (MTI) on the healthy side and pathological side
- Secondary Outcome Measures
Name Time Method velocity of shear wave in m.s-1 up to 2 months shear wave velocity on the healthy side and pathological side
Ultrasound Texture Index (UTI) up to 2 months Ultrasound Texture Index (UTI) on the healthy side and pathological side
Trial Locations
- Locations (1)
Chu Tours
🇫🇷Tours, France