Reproducibility of hemodynamic and respiratory parameters using the PiCCO monitoring system in patients with post-cardiac arrest syndrome

Not Applicable

• Conditions: Patients with post-cardiac arrest syndrome

• Registration Number: JPRN-UMIN000003221
• Lead Sponsor: Aizu chuo hospital

Brief Summary

Anaesthesia 2012, 67, 236 The aim of the present study was to determine the precision of the PiCCO® system for post-cardiac arrest patients who underwent therapeutic hypothermia. The precision of the measurements for cardiac output, global end-diastolic volume, extravascular lung water and the pulmonary vascular permeability index was assessed using the least significant change; this was regarded as precise when less than 15%. A total of 462 measurement sets were prospectively performed on 88 patients following successful resuscitation after cardiac arrest. Using the mean value of three injections for a measurement, the least significant change for the cardiac output, global end-diastolic volume, extravascular lung water and pulmonary vascular permeability index measurements were found to be 7.8%, 8.5%, 7.8% and 12.1%, respectively. No significant differences between hypothermia (n = 150) and non-hypothermia (n = 312) were found. The PiCCO-derived variables were found to be precise for post-cardiac arrest patients even under conditions of varying body temperature.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-02-21
• Study Completion: 2010-07-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients aged below 15 2)Patients in cardiac arrest associated with terminal stage of cancer. 3)Patients in cardiac arrest due to cerebrovascular disease. 4)Patients in cardiac arrest due to aortic dissection or aortic aneurysm 5)Family or other agents refuse to the registry of patient.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Investigate the intraclass correlation coefficients of Cardiac Output, Global End Diastolic Volume, ExtraVascular Lung Water, Pulmonary Vascular Permeability Index obtained from the PiCCO monitoring system in patient with post-cardiac arrest syndrome.