Computed tomography versus exercise testing in suspected coronary artery disease
Completed
- Conditions
- Coronary artery disease10011082
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 1250
Inclusion Criteria
Stable symptoms of hest pain/dyscomfort or dyspnea that is possibly the result of coronary artery disease.
Age >18 yrs, ability and willingness to provide infromed consent
Exclusion Criteria
A history of surgical or percutaneous coronary revascularization, or non-revascularized angiographic obstructive coronary artery disease (>50% diameter reduction).
Normal invasive coronary angiography or stress imaging less than 1 years ago.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>a) Absence of chest pain at 1 year<br /><br>b) Diagnostic yield of high-risk coronary artery disease</p><br>
- Secondary Outcome Measures
Name Time Method <p>Absence of chest pain at 3 and 5 years<br /><br>Quality of life at 1, 3, 5 years<br /><br>Time and cost until diagnosis<br /><br>Proportion of invasive catheterizations followed by a revascularization<br /><br>procedure<br /><br>Overall costs: diagnostics, therapy at 1, 3, 5 years.<br /><br>Cost-effectiveness (including non-medical costs, including those related to<br /><br>lost productivity)<br /><br>Event-free survival, composite endpoint: death, myocardial infarction, CVA,<br /><br>UAP, ED visits, late revascularizations.<br /><br>Radiation exposure</p><br>