Unravelling the Interplay of Weight Stigma and Pregnancy Outcomes: A Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 800
- 主要终点
- Proportion of women diagnosed with gestational diabetes mellitis by 34 weeks gestation
研究概览
简要总结
The goal of this prospective cohort study is to investigate the contribution of stigma and discrimination due to body size to adverse pregnancy outcomes. We also aim to explore the role of psychological and social factors in this relationship. The specific objectives of this study are:
Objective 1: Explore weight stigma as a mediator of the association between BMI ≥30 kg/m2 and adverse pregnancy outcomes.
Objective 2: Explore confounding factors not previously considered such as weight cycling, trauma, eating disorders, and internalised weight bias as mediators in the relationship between obesity and adverse pregnancy outcomes.
详细描述
The specific research questions for each objective are:
Objective 1 RQ1.1: Does weight stigma experienced during pregnancy in a healthcare setting reported up to 34 weeks gestation mediate the association between pre-pregnancy obesity (BMI ≥30) and gestational diabetes mellitis (GDM) (primary outcome)?
RQ1.2: Does weight stigma experienced during pregnancy in a healthcare setting reported up to 34 weeks gestation mediate the association between pre-pregnancy obesity (BMI ≥30) and (i) induction of labour; (iv) mode of birth; (ii) gestational hypertension (any); (iii) infant birth weight; and (iv) establishment of breastfeeding by 6 weeks postpartum (secondary outcomes)?
Objective 2:
RQ2.1: Do weight cycling, history of trauma, history of eating disorders, and internalised weight bias explain any of the variance in the mediation relationships described above?
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant between 10-22 weeks' gestation
- •Greater or equal than 18 years of age
- •Booked to give birth at Adelaide Women's and Children's Hospital or Royal Women's and Children's Brisbane
- •Access to the Internet to complete the survey
- •Consents to the extraction of hospital electronic medical record data about the woman and relevant to the study.
- •Ability to read and understand English
排除标准
- •Pregnant with multiple gestation
- •Insufficient English language skills to consent and complete the questionnaires.
结局指标
主要结局
Proportion of women diagnosed with gestational diabetes mellitis by 34 weeks gestation
时间窗: 34 weeks
Measuring the number of women reporting a diagnosis of gestational diabetes mellitis by 34 weeks gestation as assessed via self-reported measures and chart review.
次要结局
- Proportion of women experiencing induction of labour(6 weeks postpartum)
- Infant birth weight (in grams) reported by mothers for their most recent infant(6 weeks postpartum)
- Proportion of women reporting each mode of birth (i.e., vaginal birth, caesarean section, assisted vaginal birth, or other)(6 weeks postpartum)
- Proportion of women who reported experiencing gestational hypertension in their most recent pregnancy(6 weeks postpartum)
- Proportion of women currently breastfeeding their infant reported by mothers at 6-weeks postpartum(6 weeks postpartum)