Effect of IVF culture medium on health of IVF childre
Completed
- Conditions
- In vitro fertilization (IVF)Culture medium / Kweek mediumCardiometabolic health / cardiometabole gezondheidGrowth / groei
- Registration Number
- NL-OMON27714
- Lead Sponsor
- Academic hospital Maastricht
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 731
Inclusion Criteria
IVF group: born after an IVF treatment at the MUMC applied in the period July 2003 – December 2006
CONTROL: 9 years old, singleton
Exclusion Criteria
IVF group: Born after preimplantation genetic diagnosis (PGD)
CONTROL1:conceived by any form of assisted reproduction
Study & Design
- Study Type
- Not specified
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ength, height, skinfold thickness, blood pressure, endothelial function, lipid profile in blood, cortisol level
- Secondary Outcome Measures
Name Time Method DNA methylation
Related Research Topics
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What molecular mechanisms link IVF culture medium composition to cardiometabolic health outcomes in offspring?
How does IVF culture medium compare to standard-of-care in influencing long-term growth patterns of IVF children?
Are specific biomarkers in IVF culture medium predictive of cardiometabolic risks in later childhood development?
What adverse events are associated with prolonged exposure to IVF culture media and how are they managed clinically?
What alternative culture media or combination approaches are being explored to optimize IVF child health outcomes?