NCT02513862已完成不适用
Prospective Randomized Trial of Autologous Platelet Rich Plasma in Reducing Allogeneic Transfusions During Aortic Surgery Under Deep Hypothermic Circulatory Arrest
Hongwen Ji1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2015年5月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- total perioperative allogenic transfusions of platelet and fresh frozen plasma
研究概览
简要总结
The purpose of this study is to determine whether autologous platelet rich plasma (APRP)is effective in reducing allogeneic blood transfusions during aortic surgery using deep hypothermic circulatory arrest.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing elective or emergency aortic surgery using deep hypothermic circulatory arrest、
- •preoperative platelet counts>150000000000/L、
- •preoperative hematocrit>33%、
- •without recent anticoagulants less than 5 days
排除标准
- •preoperative coagulation disorder
- •severe renal and liver dysfunction
- •preoperative hemodynamic instability
结局指标
主要结局
total perioperative allogenic transfusions of platelet and fresh frozen plasma
时间窗: on the 7th day postoperatively
次要结局
- rate of reexploration for bleeding(on the 7th day postoperatively)
- postoperative blood loss(on the 7th day postoperatively)
研究者
Hongwen Ji
professor of medicine
Chinese Academy of Medical Sciences, Fuwai Hospital
研究点 (1)
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