Prospective Randomized Trial of Autologous Platelet Rich Plasma in Reducing Allogeneic Transfusions During Aortic Surgery Under Deep Hypothermic Circulatory Arrest

Hongwen Ji1 site in 1 country80 target enrollmentMay 2015

ConditionsC.Surgical Procedure; Cardiac

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: C.Surgical Procedure; Cardiac
Sponsor: Hongwen Ji
Enrollment: 80
Locations: 1
Primary Endpoint: total perioperative allogenic transfusions of platelet and fresh frozen plasma
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether autologous platelet rich plasma (APRP)is effective in reducing allogeneic blood transfusions during aortic surgery using deep hypothermic circulatory arrest.

Registry

clinicaltrials.gov

Start Date

May 2015

End Date

October 2016

Last Updated

9 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Hongwen Ji

Responsible Party

Sponsor Investigator

Principal Investigator

Hongwen Ji

professor of medicine

Chinese Academy of Medical Sciences, Fuwai Hospital

Eligibility Criteria

Inclusion Criteria

•patients undergoing elective or emergency aortic surgery using deep hypothermic circulatory arrest、
•preoperative platelet counts\>150000000000/L、
•preoperative hematocrit\>33%、
•without recent anticoagulants less than 5 days