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Clinical Trials/NCT04099394
NCT04099394
Active, not recruiting
Not Applicable

Randomized Controlled Trial of Group-Based Exercise and Behavioral Health Skills Training for Older Adults with Painful Knee Osteoarthritis

University of Washington1 site in 1 country280 target enrollmentOctober 30, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteo Arthritis Knee
Sponsor
University of Washington
Enrollment
280
Locations
1
Primary Endpoint
Average Number of Steps per day
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

This clinical trial will determine the added benefit of combining exercise and behavioral health education (versus exercise and aging and health education) to improve physical activity in community-dwelling older adults who have painful knee osteoarthritis (OA).

Detailed Description

Knee osteoarthritis (OA) is a highly prevalent, leading cause of pain that limits physical functioning in older adults. Although clinical practice guidelines recommend physical exercise for managing symptoms of knee OA, several systematic reviews indicate that exercise intervention studies provide only short-term benefits (lasting 6 months) for knee OA. Many older adults with painful knee OA return to sedentary lifestyles when structured exercise programs end6. Efforts to increase and sustain physical activity in this population will require promoting self-regulatory skills to develop confidence to maintain an active lifestyle and manage symptoms that often limit activity. Therefore, we developed a group-based behavioral health (BH) program for older adults with painful knee OA that complements Enhance Fitness (EF) - a multicomponent, community-based exercise program for older adults, involving balance, strength, and endurance training. The Behavioral Health (BH) program will have 10, 1-hour weekly classes spread over 4 months, while the Health Education (HE) program will be equally matched for attention with classes on aging and health. In parallel with BH/HE programs, all study subjects will participate in Enhance Fitness (EF) exercise classes that will be held for 1-hour, 3 times a week for 4 months. EF+BH intervention (versus EF+HE) improves physical activity, pain, physical function, and other outcomes in older adults with knee OA. Due to the COVID-19 pandemic, all interventions transitioned to remote delivery in 2020.

Registry
clinicaltrials.gov
Start Date
October 30, 2019
End Date
January 31, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Kushang Patel

Research Associate Professor: School of Medicine: Anesthesiology and Pain Medicine

University of Washington

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Average Number of Steps per day

Time Frame: 4 months,10 months

Participant's average number of steps per day will be measured by a thigh mounted accelerometer (acitvPAL) worn for 1 week.

Secondary Outcomes

  • Fatigue(4 months, 10 months)
  • Study Specific Treatment Satisfaction Questionnaire(4 months, 10 months)
  • Patient Global Impression of Change(4 months, 10 months)
  • Knee Pain and Function(4 months, 10 months)
  • Timed Up and Go Test(4 months, 10 months)
  • 6 Minute Walk Test(4 months, 10 months)
  • Short Physical Performance Battery(4 months, 10 months)

Study Sites (1)

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