跳至主要内容
临床试验/CTRI/2024/04/065435
CTRI/2024/04/065435尚未招募不适用

Internal jugular vein collapsibility as a predictor for hypotension after spinal anaesthesia– a prospective observational study

Seth GS Medical College and KEM hospital1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2024年4月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
110
试验地点
1
主要终点
To determine the efficacy of ultrasonographic measurements of IJV in predicting hypotension after giving spinal anaesthesia.

研究概览

简要总结

Hypotension after spinal anesthesia is a common event in routine anaesthesia practice, with a reported incidence of up to 90% (1). Although advanced age and sensory block above fifth thoracic vertebrae( T5 ) has been reported as the most important causes of post spinal hypotension, the presence of low intravascular volume related to chronic systemic diseases, poor physical condition, medications, and prolonged fasting time is also a well-known predisposing factor for this complication. (2,3) Severe or protracted intraoperative hypotension increases the risk of postoperative mortality and the emergence of critical diseases such as acute myocardial infarction, stroke, heart failure, and kidney failure.(4,5,6) Post spinal hypotension can be prevented by a number of treatment approaches, including preventive intravenous fluid replenishment and by giving vasopressors . However, most of them are ineffective and they have risky side effects, particularly in individuals who already have underlying cardiac and pulmonary disorders (7, 8).Therefore, adequate intravascular volume measurement before giving anaesthesia is crucial for preventing or minimizing such hypotensive episodes that can cause major issues. Even though central venous catheterization is quite effective in predicting intravascular volume status, its usage is constrained, particularly in elective, quick, or straightforward operations, due to its invasiveness, time-consuming nature, and potential associated problems. Therefore, non-invasive and straightforward techniques like sonographic examination of the Internal Jugular Vein (IJV) and Inferior Vena Cava (IVC) have become more popular in recent years (9, 10). There are many clinical researches that has looked into the usefulness of sonographic assessments of IVC in predicting intravascular volume prior to spinal anaesthesia ( 1,3,11). But very few researches has been done to determine if IJV ultrasonography can accurately predict post spinal hypotension.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • ASA I -III BMI less than 30 kg/m2 Posted for elective surgeries under Spinal Anaesthesia Willing to participate in the study.

排除标准

  • History of cardiovascular or respiratory disorders Not willing to participate in study.

结局指标

主要结局

To determine the efficacy of ultrasonographic measurements of IJV in predicting hypotension after giving spinal anaesthesia.

时间窗: the outcomes will be assessed at baseline before spinal anesthesia and then after 0 minutes 10 minutes 20 minutes 30 minutes up to 1 hour.

次要结局

未报告次要终点

研究者

发起方
Seth GS Medical College and KEM hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Deepa Ghanashyam Kane

Seth GS Medical College and KEM hospital

研究点 (1)

Loading locations...

相似试验