Trust Game and Placebo Response

Not Applicable

Completed

• Conditions: Trust; Placebo Effect; Pain

• Registration Number: NCT02578212
• Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary

In the proposed study, investigators aim to investigate the role of interpersonal trust in the conditioned placebo analgesia process with healthy male subjects in a standardized experimental heat pain paradigm.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2015-10-12
• Study First Submitted QC: 2015-10-14
• Study First Posted: 2015-10-16
• Primary Completion: 2016-03
• Study Completion: 2016-03
• Status Verified: 2016-04
• Last Update Submitted: 2016-04-07
• Last Update Posted: 2016-04-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 106

Inclusion Criteria

• Men: age between 18 and 40 years old
• Healthy by self-report statement, thus no known current or chronic somatic diseases or psychiatric disorders
• Right-handedness (Oldfield, 1971)
• Willing to participate in study

Exclusion Criteria

• Any acute or chronic disease (chronic pain, hypertension, heart disease, renal disease, liver disease, diabetes) as well as skin pathologies, neuropathies or nerve entrapment symptoms, sensory abnormalities affecting the tactile or thermal modality
• Current medications (psychoactive medication, narcotics, intake of analgesics) or being currently in psychological or psychiatric treatment
• Insufficient German language skills to understand the instructions
• Previous participation in studies using pain assessment (threshold and tolerance) with Peltier Devices
• Daily consumption of more than three alcoholic standard beverages per day (a standard alcoholic beverage is defined as either 3dl beer or 1 dl wine or 2cl spirits
• Current or regular drug consumption (THC, cocaine, heroin, etc.)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Visual analogue scale (VAS) rating (Intensity + unpleasantness of pain)	2 hours

Secondary Outcome Measures

Name	Time	Method
Visual analogue scale (VAS) rating (trust)	2 hours
State-Trait-Anxiety (STAI- X1)	2 hours
State Trait Anger Expression (STAXI)	2 hours
Questionnaire about expectations (Erwartungsfragebogen)	2 hours
sociodemographic questionnaire (Soziodemographischer Fragebogen (SES))	2 hours
Questionnaire about Self-assessment of partnership binding (Bochumer Bindungsfragebogen - BoBi)	2 hours
State-Trait-Anxiety (STAI-X2 )	2 hours
Questionnaire about the investigator (Fragebogen zum Versuchsleiter	2 hours

Trial Locations

Locations (1)

University of Basel; 🇨🇭 Basel, Switzerland