Based on cognitive neuropsychology, explore the mechanism of fMRI/ERP bimodal brain network in the treatment of primary insomnia with Chaihu Keel Oyster Decoctio
- Conditions
- insomnia
- Registration Number
- ITMCTR2200006593
- Lead Sponsor
- Jiangsu Province Hospital of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Accord with the diagnosis of primary chronic insomnia;
2. PSQI score = 7;
3. Age 20-60 years old;
4. Not taking sedative and hypnotic drugs within a week, and not taking antidepressants and antipsychotics within a month. No psychoactive substances such as alcohol, coffee and cigarettes were ingested within 2 hours before the examination;
5. Clear mind, no other cognitive impairment, and can tolerate 30 minutes of magnetic resonance examination;
6. Sign informed consent according to ethical requirements.
1. Abnormal binocular vision (or corrected vision) and hearing;
2. History of other mental diseases (depression, generalized anxiety disorder, panic disorder, bipolar disorder, mania, schizophrenia, etc.), HAMD>7, HAMA=7;
3. Other sleep disorders, such as sleep apnea, restless legs syndrome, etc;
4. Severe depression with suicidal tendency;
5. Serious physical diseases (thyroid disease, serious heart disease, malignant tumor, etc.);
6. History of alcohol, coffee, drug abuse, serious head injury and surgery;
7. Daytime obvious pathological sleepiness;
8. Night shift, jet lag, lactation and other circadian sleep rhythm disorders.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PSQI;
- Secondary Outcome Measures
Name Time Method MoCA;MMSE;